Head-to-head · Cost-Efficiency Index
SexyMD vs TMates
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
SexyMD
Readers willing to commit 48 weeks up front, where the advertised figure is the one actually charged.
Visit SexyMDTMates
Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Visit TMatesThe verdict
SexyMD and TMates tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers, so choose on fit. SexyMD: Readers willing to commit 48 weeks up front, where the advertised figure is the one actually charged. TMates: Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs SexyMD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | SexyMD | TMates |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $269/moOn the four-week plan (the site's "from $199" is the 48-week commitment rate) | $249/moMonth to month, same price at every dose, compounded |
| Tirzepatide / mo | $369/moOn the four-week plan (the site's "from $299" is the 48-week commitment rate) | $297/moMonth to month, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $3,49713 charges | $2,988 |
| Tirzepatide / yr (modeled) | $4,79713 charges | $3,564 |
| Coverage | 47 states | Not published ("most states") |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Yes |
| Rank here | #159 | #160 |
SexyMD
68/100Where the value is
- Publishes a full four-rung price table for each molecule on its product pages, before any intake
- States both pharmacy classes it uses and discloses that a prescription may be routed to, and transferred between, any pharmacy in that network
- Names the professional entities its prescribers work through, rather than referring only to licensed providers
The tradeoffs
- Every headline on the site quotes the 48-week rate: "from $199 per month" against a four-week price of $269, and "from $299" against $369, with an asterisk that resolves to no footnote
- The same footer block says both "available in all 50 states" and "available in all states except Arkansas, Mississippi, and New Jersey", on all eleven pages
TMates
68/100Where the value is
- Each product page lists every plan: semaglutide is $249 for one month, $650 for three, $1,050 for six and $1,900 for twelve; tirzepatide is $297, $800, $1,299 and $1,999
- The price covers the medication, telemedicine visits and coaching, and stays the same at every dose
- Semaglutide comes as a weekly injection or an oral option, and brand Wegovy or Zepbound can be prescribed for $99 a month to fill at your own pharmacy
The tradeoffs
- The "from $158" and "from $167" category prices are 12-month prepaid rates; month to month is $249 and $297
- No refund once your prescription is sent to the pharmacy
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.