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Alternatives

Alternatives to Cost Plus Drugs

Cost Plus Drugs scores 64/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.

Read the Cost Plus Drugs review →CoreAge Rx vs Cost Plus Drugs →

Not available to order. Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first. The programs below sell GLP-1 treatment to patients directly.

Cost Plus Drugs at a glance

Semaglutide
$279/moBrand Ozempic
Tirzepatide
Not disclosed
Coverage
All 50 states
Brand-name GLP-1s
Yes
Oral option
No
Pricing verified
October 2026

6 of the 8 programs below list semaglutide for less than Cost Plus Drugs's $279 a month.

Mark Cuban's transparent-pricing online pharmacy.

Best for: Shoppers who want brand-name Ozempic from an online pharmacy that publishes its markup.

What Cost Plus Drugs does well

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
  • Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
  • Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing

Why readers look for an alternative

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships
  • No compounded semaglutide or tirzepatide — brand only
  • No clinical follow-up — side-effect monitoring falls to your prescribing clinician
  1. Partner
    01A

    CoreAge Rx

    CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with Cost Plus Drugs: $180/mo less for semaglutide · compounded only, no brand-name GLP-1s

    Visit CoreAge Rx CoreAge Rx vs Cost Plus Drugs →
  2. 02C

    MyDrHank

    Partner

    Every price this site advertises is a twelve-month prepay rate — its price display returns the cheapest term by design — so the real month-to-month cost is $249-$349, not the "from $171" on the page.

    Sema
    $249/moOral, $259/mo injectable (yearly prepay: $171 / $178)
    Tirz
    $349/moMonth-to-month ($240/mo only on a year prepaid)
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Cost Plus Drugs: $30/mo less for semaglutide · compounded only, no brand-name GLP-1s · offers an oral option

    Visit MyDrHank MyDrHank vs Cost Plus Drugs →
  3. 03C

    Collective

    Partner

    Collective sells compounded semaglutide at $59 and tirzepatide at $69 a month, both genuinely medication prices, on top of a $199 annual membership that is required, auto-renewing and not refundable.

    Sema
    $59/moFor the medication, plus a required $199/year membership billed separately
    Tirz
    $69/moFor the medication, plus the same required $199/year membership
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Cost Plus Drugs: $220/mo less for semaglutide · compounded only, no brand-name GLP-1s

    Visit Collective Collective vs Cost Plus Drugs →
  4. 04C

    Luvo Health

    Partner

    Luvo charges $209 every four weeks for compounded semaglutide and $249 for tirzepatide, with half off the first delivery and brand-name Ozempic or Zepbound available.

    Sema
    $209 per 4 weeksInjection, compounded
    Tirz
    $249 per 4 weeksInjection, compounded
    Coverage
    Multi-state
    Brand
    Yes

    Compared with Cost Plus Drugs: $70/mo less for semaglutide · offers an oral option

    Visit Luvo Health Luvo Health vs Cost Plus Drugs →
  5. 05C

    MEDGm

    Partner

    MEDGm charges $299 a month for compounded semaglutide injections and $399 for tirzepatide once the $120 welcome coupon lapses, prints every plan length on its product pages, and names the four pharmacies that fill its prescriptions.

    Sema
    $299/moMonth-to-month (the advertised $179 is the first month only, after an automatically applied coupon)
    Tirz
    $399/moMonth-to-month (the advertised $279 is the first month only)
    Coverage
    All 50 states
    Brand
    Yes

    Compared with Cost Plus Drugs: $20/mo more for semaglutide · offers an oral option

    Visit MEDGm MEDGm vs Cost Plus Drugs →
  6. 06C

    Lttl

    Partner

    Lttl charges $99 every four weeks for compounded semaglutide and $149 for tirzepatide on a cancel-anytime auto-refill, with small discounts for longer supplies.

    Sema
    $99 per 4 weeksCompounded, auto-refill
    Tirz
    $149 per 4 weeksCompounded, auto-refill
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Cost Plus Drugs: $180/mo less for semaglutide · compounded only, no brand-name GLP-1s · offers an oral option

    Visit Lttl Lttl vs Cost Plus Drugs →
  7. 07C

    Willow

    Partner

    Willow is a direct-to-consumer telehealth provider offering compounded semaglutide and tirzepatide in both injectable and oral-tablet form at identical prices per format.

    Sema
    $299/moCompounded, month to month
    Tirz
    $399/moCompounded, month to month
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Cost Plus Drugs: $20/mo more for semaglutide · compounded only, no brand-name GLP-1s · offers an oral option

    Visit Willow Willow vs Cost Plus Drugs →
  8. 08C

    RNK Health

    Partner

    Compounded semaglutide from $197 a month and tirzepatide from $297, with the doctor visit, medication, supplies and shipping in one monthly price you can cancel.

    Sema
    From $197/moCompounded, month to month
    Tirz
    From $297/moCompounded, month to month
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Cost Plus Drugs: $82/mo less for semaglutide · compounded only, no brand-name GLP-1s

    Visit RNK Health RNK Health vs Cost Plus Drugs →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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