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WeighLab

Cost Plus Drugs vs Lttl

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Cost Plus Drugs

Provider comparison

Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

Semaglutide / month
$279/moBrand Ozempic
Tirzepatide / month
Not disclosed
Unavailable · Not scoredChecked October 2026

Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

Read review

Lttl

Affiliate partner

Shoppers who want a low price without prepaying, and who are fine with a refill that ships and bills every four weeks.

Semaglutide / month
$99 per 4 weeksCompounded, auto-refill
Tirzepatide / month
$149 per 4 weeksCompounded, auto-refill
Index 61/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

This pair includes a provider that is unavailable for direct GLP-1 enrollment. We do not declare a score winner or compare factor scores when either provider is unavailable.

  • Cost Plus Drugs: Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

Check the difference in state access

Cost Plus Drugs
All 50 states
Lttl
Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Cost Plus Drugs

Lttl

Semaglutide / month
Cost Plus Drugs: $279/moBrand Ozempic
Lttl: $99 per 4 weeksCompounded, auto-refill
Tirzepatide / month
Cost Plus Drugs: Not disclosed
Lttl: $149 per 4 weeksCompounded, auto-refill
Semaglutide / year (modeled)
Cost Plus Drugs: $3,348
Lttl: $1,28713 charges
Tirzepatide / year (modeled)
Cost Plus Drugs: —
Lttl: $1,93713 charges
State availability
Cost Plus Drugs: All 50 states
Lttl: Coverage not published
Oral / sublingual option listed
Cost Plus Drugs: Not listed
Lttl: Yes
Brand-name access listed
Cost Plus Drugs: Yes
Lttl: Not confirmed
Provider facts checked
Cost Plus Drugs: October 2026
Lttl: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

Review the access limitations and recorded program details. Availability comes before choosing a treatment plan.

Cost Plus Drugs

Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

Provider background

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News

What to weigh up

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships

Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

Read the full Cost Plus Drugs review

Lttl

Shoppers who want a low price without prepaying, and who are fine with a refill that ships and bills every four weeks.

Reasons to consider it

  • Every medication and supply length is priced on its plans page before checkout
  • Longer supplies trim the price only a little: semaglutide is $96, $93 or $89 per four weeks on 12-, 24- or 52-week supplies, so month to month costs you almost nothing extra
  • Named medical advisory board (pharmacist, nurse practitioner, physical therapist) rather than zero disclosure

What to weigh up

  • Billing is every four weeks, so a year is 13 charges: about $1,287 on semaglutide and $1,937 on tirzepatide
  • The struck-through $249 and $339 beside each price are not a price anyone is quoted, so ignore the "savings" figures
  • A first-month discount of up to $140 is applied automatically, so check what your second order costs

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.