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WeighLab

MEDGm vs Cost Plus Drugs

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

MEDGm

Affiliate partner

Readers who want the dispensing pharmacies and the prescribing practices named, and who will price the second month rather than the first.

Semaglutide / month
$299/moMonth-to-month (the advertised $179 is the first month only, after an automatically applied coupon)
Tirzepatide / month
$399/moMonth-to-month (the advertised $279 is the first month only)
Index 67/100 · Grade CChecked October 2026

Cost Plus Drugs

Provider comparison

Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

Semaglutide / month
$279/moBrand Ozempic
Tirzepatide / month
Not disclosed
Unavailable · Not scoredChecked October 2026

Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

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The comparison in brief

This pair includes a provider that is unavailable for direct GLP-1 enrollment. We do not declare a score winner or compare factor scores when either provider is unavailable.

  • Cost Plus Drugs: Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

MEDGm

Cost Plus Drugs

Semaglutide / month
MEDGm: $299/moMonth-to-month (the advertised $179 is the first month only, after an automatically applied coupon)
Cost Plus Drugs: $279/moBrand Ozempic
Tirzepatide / month
MEDGm: $399/moMonth-to-month (the advertised $279 is the first month only)
Cost Plus Drugs: Not disclosed
Semaglutide / year (modeled)
MEDGm: $3,588
Cost Plus Drugs: $3,348
Tirzepatide / year (modeled)
MEDGm: $4,788
Cost Plus Drugs: —
State availability
MEDGm: All 50 states
Cost Plus Drugs: All 50 states
Oral / sublingual option listed
MEDGm: Yes
Cost Plus Drugs: Not listed
Brand-name access listed
MEDGm: Yes
Cost Plus Drugs: Yes
Provider facts checked
MEDGm: October 2026
Cost Plus Drugs: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

Review the access limitations and recorded program details. Availability comes before choosing a treatment plan.

MEDGm

Readers who want the dispensing pharmacies and the prescribing practices named, and who will price the second month rather than the first.

Reasons to consider it

  • Names all four pharmacy partners in its terms, with street addresses, phone numbers and websites, and says which compounding classes they operate under
  • Names seven prescribing professional corporations on its consent page rather than referring to an unnamed medical group
  • Prices three GLP-1 routes — semaglutide injection, semaglutide tablet and tirzepatide — at one, three, six and twelve months, all on the public product pages before any intake

What to weigh up

  • The GLP-1 page's "Starting at $169" is the twelve-month rate paid upfront ($2,028), and the $179 that follows it is a first-month coupon price; month to month, semaglutide injections cost $299, tablets $369 and tirzepatide $399
  • The treatments FAQ says "your price never increases" on a plan whose price increases by $120 at the first renewal
  • The twelve-month bundle is charged upfront, renews for another full upfront year up to ten days early, and none of it is refundable once charged

Cost Plus Drugs

Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

Provider background

  • Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
  • Around $279/mo for branded Ozempic — well below typical retail list prices
  • Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News

What to weigh up

  • Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
  • Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
  • Wegovy availability has been spotty — check current stock before assuming it ships

Cost Plus Drugs is a mail-order pharmacy. It fills prescriptions but doesn't prescribe, so you need a prescriber first.

Read the full Cost Plus Drugs review

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.