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WeighLab

ShedRx (Shed) vs RxSpan MD

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

ShedRx (Shed)

Affiliate partner

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Semaglutide / month
$199/mo$159 on a 12-month plan
Tirzepatide / month
$299/mo$239 on a 12-month plan
Index 87/100 · Grade B+Checked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check ShedRx (Shed) pricing Read review

RxSpan MD

Affiliate partner

Someone who wants to compare a compounded route against brand-name Zepbound or Wegovy without leaving one provider, and who will read past the twelve-month figure.

Semaglutide / month
$249/moMonth-to-month for the injection; $219 on three months, $199 on six and $194 on twelve
Tirzepatide / month
$329/moMonth-to-month for the injection; $309 on three months, $289 on six and $269 on twelve
Index 83/100 · Grade BChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check RxSpan MD pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

ShedRx (Shed) has the higher Cost-Efficiency Index: 87/100 versus 83/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

ShedRx (Shed)

RxSpan MD

Semaglutide / month
ShedRx (Shed): $199/mo$159 on a 12-month plan
RxSpan MD: $249/moMonth-to-month for the injection; $219 on three months, $199 on six and $194 on twelve
Tirzepatide / month
ShedRx (Shed): $299/mo$239 on a 12-month plan
RxSpan MD: $329/moMonth-to-month for the injection; $309 on three months, $289 on six and $269 on twelve
Semaglutide / year (modeled)
ShedRx (Shed): $2,388
RxSpan MD: $2,988
Tirzepatide / year (modeled)
ShedRx (Shed): $3,588
RxSpan MD: $3,948
State availability
ShedRx (Shed): All 50 states
RxSpan MD: All 50 states
Oral / sublingual option listed
ShedRx (Shed): Yes
RxSpan MD: Yes
Brand-name access listed
ShedRx (Shed): Yes
RxSpan MD: Yes
Provider facts checked
ShedRx (Shed): October 2026
RxSpan MD: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Reasons to consider it

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included

What to weigh up

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • The dispensing compounding pharmacy is not publicly named

Compounded drugs are not FDA-approved. Understand the medication options.

Check ShedRx (Shed) pricing Read the full ShedRx (Shed) review

RxSpan MD

Someone who wants to compare a compounded route against brand-name Zepbound or Wegovy without leaving one provider, and who will read past the twelve-month figure.

Reasons to consider it

  • Every product and every term carries a published price, including the brand-name lane: Zepbound at $1,069, Ozempic at $1,299 and Wegovy at $1,349
  • Three ways to take it on one account: a weekly injection, a daily capsule of either molecule, or a brand-name drug
  • Names its medical group, Lion MD, with two lead physicians and their NPI numbers, and lists four dispensing pharmacies with phone numbers

What to weigh up

  • The figure a reader is most likely to meet elsewhere, around $194, is the twelve-month per-month rate; one month of the semaglutide injection is $249
  • Its semaglutide prices match Prime Doctor RX's to the dollar at every plan length, so comparing the two on price tells you little
  • Brand-name pricing is cash pricing: none of those three figures reflects insurance

Compounded drugs are not FDA-approved. Understand the medication options.

Check RxSpan MD pricing Read the full RxSpan MD review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

ShedRx (Shed)RxSpan MD
Normalized Cost/Month
ShedRx (Shed):
86/100
RxSpan MD:
72/100
Price Transparency
ShedRx (Shed):
74/100
RxSpan MD:
84/100
Nationwide Access
ShedRx (Shed):
92/100
RxSpan MD:
88/100
Formulation Options
ShedRx (Shed):
96/100
RxSpan MD:
92/100
Clinical Oversight
ShedRx (Shed):
84/100
RxSpan MD:
86/100
Contract Flexibility
ShedRx (Shed):
76/100
RxSpan MD:
80/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.