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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs ShedRx (Shed)

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade B+ · #4

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)

The verdict

Winner · CoreAge RxGrade A vs B+

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 87. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. ShedRx (Shed) still earns a B+People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
86

Price Transparency

97
74

Nationwide Access

98
92

Formulation Options

84
96

Clinical Oversight

90
84

Contract Flexibility

95
76

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxShedRx (Shed)
Cost-Efficiency Index94/10087/100
Semaglutide / mo$99/mo$199/mo ($159 on a 12-month plan)
Tirzepatide / mo$149/mo$299/mo ($239 on a 12-month plan)
Semaglutide / yr (modeled)$1,188$2,388
Tirzepatide / yr (modeled)$1,788$3,588
CoverageAll 50 statesAll 50 states
Oral / sublingualNoYes
Brand-name accessCompounded onlyYes
Rank here#1#4

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — 30 of the 371 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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