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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs RxSpan MD

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade B · #17

RxSpan MD

Someone who wants to compare a compounded route against brand-name Zepbound or Wegovy without leaving one provider, and who will read past the twelve-month figure.

Visit RxSpan MD

The verdict

Winner · CoreAge RxGrade A vs B

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 83. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. RxSpan MD still earns a BSomeone who wants to compare a compounded route against brand-name Zepbound or Wegovy without leaving one provider, and who will read past the twelve-month figure.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
72

Price Transparency

97
84

Nationwide Access

98
88

Formulation Options

84
92

Clinical Oversight

90
86

Contract Flexibility

95
80

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxRxSpan MD
Cost-Efficiency Index94/10083/100
Semaglutide / mo$99/mo$249/mo month-to-month for the injection; $219 on three months, $199 on six and $194 on twelve
Tirzepatide / mo$149/mo$329/mo month-to-month for the injection; $309 on three months, $289 on six and $269 on twelve
Semaglutide / yr (modeled)$1,188$2,988
Tirzepatide / yr (modeled)$1,788$3,948
CoverageAll 50 statesAll 50 states
Oral / sublingualNoYes
Brand-name accessCompounded onlyYes
Rank here#1#17

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — 30 of the 381 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

RxSpan MD

83/100

Where the value is

  • Every product and every term carries a published price, including the brand-name lane: Zepbound and Mounjaro at $1,069, Ozempic at $1,299 and Wegovy at $1,349
  • Five routes on one account — injection, oral capsule, orally dissolving tablet, microdose injection and brand — which is the broadest formulary of anything ranked here
  • A physician-founded program serving all 50 states

The tradeoffs

  • The storefront renders no price at all without JavaScript: the catalog is reachable, but a reader with a blocked script sees nothing
  • The figure a reader is most likely to meet elsewhere, around $194, is the twelve-month per-month rate; one month of the semaglutide injection is $249
Visit RxSpan MD

Full RxSpan MD review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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