PrescrYbe vs Independent Wellness

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

PrescrYbe

Provider comparison

Shoppers who want an injection, an oral tablet or a microdose plan priced up front on one page, and who budget by the four-week cycle rather than the month.

Semaglutide / month: $249Every 4 weeks (compounded injection; oral $279, microdose $179)
Tirzepatide / month: $339Every 4 weeks (compounded injection; microdose $179)

Index 74/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check PrescrYbe pricing Read review

Independent Wellness

Provider comparison

Patients in its 20 covered states who want ongoing care from the same nurse practitioner.

Semaglutide / month: $199/moOngoing compounded plan; $99 first month
Tirzepatide / month: $299/moOngoing compounded plan; $199 first month

Index 73/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Independent Wellness pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

PrescrYbe has the higher Cost-Efficiency Index: 74/100 versus 73/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

PrescrYbe: All 50 states + DC
Independent Wellness: 20 states (published list)

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

PrescrYbe

Independent Wellness

Semaglutide / month: PrescrYbe: $249Every 4 weeks (compounded injection; oral $279, microdose $179); Independent Wellness: $199/moOngoing compounded plan; $99 first month

Tirzepatide / month: PrescrYbe: $339Every 4 weeks (compounded injection; microdose $179); Independent Wellness: $299/moOngoing compounded plan; $199 first month

Semaglutide / year (modeled): PrescrYbe: $3,23713 charges; Independent Wellness: $2,388

Tirzepatide / year (modeled): PrescrYbe: $4,40713 charges; Independent Wellness: $3,588

State availability: PrescrYbe: All 50 states + DC; Independent Wellness: 20 states (published list)

Oral / sublingual option listed: PrescrYbe: Yes; Independent Wellness: Yes

Brand-name access listed: PrescrYbe: Not confirmed; Independent Wellness: Yes

Provider facts checked: PrescrYbe: October 2026; Independent Wellness: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

PrescrYbe

Shoppers who want an injection, an oral tablet or a microdose plan priced up front on one page, and who budget by the four-week cycle rather than the month.

Reasons to consider it

Five GLP-1 plans are priced on the weight-loss page before any questionnaire: semaglutide injection $249, tirzepatide injection $339, oral semaglutide $279, and microdose semaglutide or tirzepatide at $179
Offers an oral semaglutide formulation as well as weekly injections
Names its clinical partner, OpenLoop Health, and says plans are evaluated by board-certified clinicians, with follow-ups to adjust dosing and manage side effects

What to weigh up

Every price is charged per four weeks, not per month, so a year is 13 charges: $3,237 for semaglutide injections rather than 12 × $249
Cancellations must reach support at least 72 hours before the next billing date, and a cycle that has already been charged is not refunded
The dispensing pharmacy is not named; the site says only that a licensed pharmacy partner fills prescriptions

Compounded drugs are not FDA-approved. Understand the medication options.

Check PrescrYbe pricing Read the full PrescrYbe review

Independent Wellness

Patients in its 20 covered states who want ongoing care from the same nurse practitioner.

Reasons to consider it

Care from Bonnie Lea Davis, a board-certified family nurse practitioner
Public ongoing prices: $199 for semaglutide and $299 for tirzepatide, with lower first-month offers
Injection and oral options, with brand-name routes listed separately

What to weigh up

The advertised $99/$199 figures cover the first month; ongoing plans cost $199/$299
Service is limited to 20 states; check the published list before starting
Lab inclusion depends on the selected program, so confirm any extra testing costs

Compounded drugs are not FDA-approved. Understand the medication options.

Check Independent Wellness pricing Read the full Independent Wellness review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PrescrYbeIndependent Wellness

Normalized Cost/Month: PrescrYbe:
56/100; Independent Wellness:
71/100

Price Transparency: PrescrYbe:
86/100; Independent Wellness:
86/100

Nationwide Access: PrescrYbe:
86/100; Independent Wellness:
52/100

Formulation Options: PrescrYbe:
77/100; Independent Wellness:
90/100

Clinical Oversight: PrescrYbe:
73/100; Independent Wellness:
82/100

Contract Flexibility: PrescrYbe:
67/100; Independent Wellness:
55/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.