Head-to-head · Cost-Efficiency Index
CoreAge Rx vs PrescrYbe
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CoreAge Rx
Anyone who wants one flat monthly price they can plan a full year around, on either molecule, without signing a contract.
Visit CoreAge RxPrescrYbe
Shoppers who want an injection, an oral tablet or a microdose plan priced up front on one page, and who budget by the four-week cycle rather than the month.
Visit PrescrYbeThe verdict
CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 74. CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee. PrescrYbe still earns a C — Shoppers who want an injection, an oral tablet or a microdose plan priced up front on one page, and who budget by the four-week cycle rather than the month.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CoreAge Rx | PrescrYbe |
|---|---|---|
| Cost-Efficiency Index | 94/100 | 74/100 |
| Semaglutide / mo | $99/mo | $249Every 4 weeks (compounded injection; oral $279, microdose $179) |
| Tirzepatide / mo | $149/mo | $339Every 4 weeks (compounded injection; microdose $179) |
| Semaglutide / yr (modeled) | $1,188 | $3,23713 charges |
| Tirzepatide / yr (modeled) | $1,788 | $4,40713 charges |
| Coverage | All 50 states | All 50 states + DC |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #1 | #81 |
CoreAge Rx
94/100Where the value is
- One price at every dose: semaglutide is $99 from 0.25 mg up to 2.5 mg, and tirzepatide is $149 from 2.5 mg up to 15 mg
- No membership fee, no insurance needed and no long-term contract, and the price you lock in at checkout stays put as your dose rises
- If the doctor decides a prescription isn't right for you, CoreAge refunds the medication portion of your payment
The tradeoffs
- Not the lowest price around: 35 of the 434 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
- You pay before the doctor reviews your case, and if you aren't approved the FAQ promises a 100% refund while the refund policy keeps a $50 to $100 consultation fee
PrescrYbe
74/100Where the value is
- Five GLP-1 plans are priced on the weight-loss page before any questionnaire: semaglutide injection $249, tirzepatide injection $339, oral semaglutide $279, and microdose semaglutide or tirzepatide at $179
- Offers an oral semaglutide formulation as well as weekly injections
- Names its clinical partner, OpenLoop Health, and says plans are evaluated by board-certified clinicians, with follow-ups to adjust dosing and manage side effects
The tradeoffs
- Every price is charged per four weeks, not per month, so a year is 13 charges: $3,237 for semaglutide injections rather than 12 × $249
- Cancellations must reach support at least 72 hours before the next billing date, and a cycle that has already been charged is not refunded
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.