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WeighLab

Calibrate Health vs ZYP Medical

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Calibrate Health

Provider comparison

Insured shoppers who want a year of coaching built around a brand-name GLP-1, not the cheapest sticker price.

Semaglutide / month
Not disclosed
Tirzepatide / month
Not disclosed
Index 63/100 · Grade CChecked August 2026

ZYP Medical

Provider comparison

Readers in one of seven served states who want direct clinician contact and will confirm the consultation charge and refill price.

Semaglutide / month
Ongoing rate not published ($399 initial 10-week compounded injection course; plus a separate fee for consultation if applicable)
Tirzepatide / month
$250/moOral ODT (30-day supply, compounded); injectable starter $450 for 2 months; plus a separate fee for consultation if applicable
Index 63/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 63/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

Calibrate Health
All 50 states
ZYP Medical
7 states: NE, IA, SD, MN, KS, CO and AZ

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Calibrate Health

ZYP Medical

Semaglutide / month
Calibrate Health: Not disclosed
ZYP Medical: Ongoing rate not published ($399 initial 10-week compounded injection course; plus a separate fee for consultation if applicable)
Tirzepatide / month
Calibrate Health: Not disclosed
ZYP Medical: $250/moOral ODT (30-day supply, compounded); injectable starter $450 for 2 months; plus a separate fee for consultation if applicable
Semaglutide / year (modeled)
Calibrate Health: —
ZYP Medical: —
Tirzepatide / year (modeled)
Calibrate Health: —
ZYP Medical: $3,000
State availability
Calibrate Health: All 50 states
ZYP Medical: 7 states: NE, IA, SD, MN, KS, CO and AZ
Oral / sublingual option listed
Calibrate Health: Not listed
ZYP Medical: Yes
Brand-name access listed
Calibrate Health: Yes
ZYP Medical: Not confirmed
Provider facts checked
Calibrate Health: August 2026
ZYP Medical: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Calibrate Health

Insured shoppers who want a year of coaching built around a brand-name GLP-1, not the cheapest sticker price.

Reasons to consider it

  • Year-long 1:1 video coaching, dietitian support, and a behavior-change curriculum — a materially deeper clinical wrap than transactional telehealth competitors
  • Insurance-navigation team works to get medication cost down to '$25/month or less' for members with qualifying commercial coverage
  • 10%+ weight-loss money-back guarantee is advertised on the pricing page itself, not buried in fine print

What to weigh up

  • The $199/month headline is the coaching fee alone — medication is billed on top, and full cash-pay brand pricing (for anyone without qualifying insurance) is never disclosed on the pricing page
  • 3-month minimum commitment ($597 billed as $199/mo) before the plan becomes cancelable month-to-month
  • No compounded medication option at all, so a member whose insurance denies GLP-1 coverage faces full brand-name pricing with no cheaper fallback on this platform

ZYP Medical

Readers in one of seven served states who want direct clinician contact and will confirm the consultation charge and refill price.

Reasons to consider it

  • Names Josh Peterson, FNP-C as the treating clinician
  • Publishes full injection starter totals and a thirty-day oral ODT price
  • Names its seven states and Gretna, Nebraska office

What to weigh up

  • The semaglutide starter total does not establish a continuing monthly injection price
  • The weight-loss page advertises a free first consultation while the site footer lists $75 and $39.99 visits; confirm which applies
  • Refill cost depends on dose and order size

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Calibrate HealthZYP Medical
Normalized Cost/Month
Calibrate Health:
45/100
ZYP Medical:
47/100
Price Transparency
Calibrate Health:
54/100
ZYP Medical:
86/100
Nationwide Access
Calibrate Health:
86/100
ZYP Medical:
42/100
Formulation Options
Calibrate Health:
53/100
ZYP Medical:
77/100
Clinical Oversight
Calibrate Health:
93/100
ZYP Medical:
85/100
Contract Flexibility
Calibrate Health:
55/100
ZYP Medical:
51/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.