Head-to-head · Cost-Efficiency Index
CoreAge Rx vs ZYP Medical
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CoreAge Rx
Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.
Visit CoreAge RxZYP Medical
Cost-first shoppers who want men in IA, NE, SD, MN, KS, CO or AZ wanting a low starter rate with an oral needle-free option.
Visit ZYP MedicalThe verdict
CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 56. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. ZYP Medical still earns a C — Cost-first shoppers who want men in IA, NE, SD, MN, KS, CO or AZ wanting a low starter rate with an oral needle-free option.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CoreAge Rx | ZYP Medical |
|---|---|---|
| Cost-Efficiency Index | 94/100 | 56/100 |
| Semaglutide / mo | $99/mo | $150/mo (starting dose, 3 month plan, plus a separate fee, compounded) |
| Tirzepatide / mo | $149/mo | $233/mo (starting dose, 3 month plan, plus a separate fee, compounded) |
| Semaglutide / yr (modeled) | $1,188 | $1,800 |
| Tirzepatide / yr (modeled) | $1,788 | $2,796 |
| Coverage | All 50 states | 6 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #1 | #333 |
CoreAge Rx
94/100Where the value is
- Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
- Both compounded semaglutide and tirzepatide on one account at published prices
- Available in all 50 states — no coverage gamble
The tradeoffs
- Not the rock-bottom sticker price — 30 of the 381 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
- No FDA-approved brand-name option (compounded only)
ZYP Medical
56/100Where the value is
- Offers a genuine needle-free oral tirzepatide (ODT) option, not just injectable
- Consult fee is disclosed and itemized ($50, or $29.99 for a shorter returning-patient visit)
- Recently expanded to 7 states (added Minnesota)
The tradeoffs
- Advertised $150/$233 prices are explicitly labeled 'starter plans (initial 3 months)' — what they become after 3 months is not published anywhere on the site
- One-time consult fee ($29.99-$50) is charged on top of the medication price and is non-refundable once the visit occurs
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.