Alloy vs Rx.com

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Alloy

Provider comparison

Women who want menopause care and GLP-1 weight management under the same physician and don't mind a recurring care fee.

Semaglutide / month: $169/moStarting dose, compounded
Tirzepatide / month: $199/moStarting dose, compounded

Index 77/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Alloy pricing Read review

Rx.com

Provider comparison

Someone who will judge it by the plan card rather than the banner, and who values no auto-renewal and a named pharmacy over the lowest sticker.

Semaglutide / month: $175/moMonth-to-month; $165 on three months, $146 on six and $99 on twelve, prepaid
Tirzepatide / month: $285/moMonth-to-month; $265 on three months, $259 on six and $149 on twelve, prepaid

Index 77/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Rx.com pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 77/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

Alloy: 48 states; compounded options restricted in 4 more states and DC
Rx.com: 47 states on its program page; product pages say 49

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Alloy

Rx.com

Semaglutide / month: Alloy: $169/moStarting dose, compounded; Rx.com: $175/moMonth-to-month; $165 on three months, $146 on six and $99 on twelve, prepaid

Tirzepatide / month: Alloy: $199/moStarting dose, compounded; Rx.com: $285/moMonth-to-month; $265 on three months, $259 on six and $149 on twelve, prepaid

Semaglutide / year (modeled): Alloy: $2,028; Rx.com: $2,100

Tirzepatide / year (modeled): Alloy: $2,388; Rx.com: $3,420

State availability: Alloy: 48 states; compounded options restricted in 4 more states and DC; Rx.com: 47 states on its program page; product pages say 49

Oral / sublingual option listed: Alloy: Yes; Rx.com: Not listed

Brand-name access listed: Alloy: Yes; Rx.com: Not confirmed

Provider facts checked: Alloy: October 2026; Rx.com: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Alloy

Women who want menopause care and GLP-1 weight management under the same physician and don't mind a recurring care fee.

Reasons to consider it

Brand and compounded medication options are listed with published starting prices
The $99 care fee includes physician messaging, dose adjustments and delivery
Menopause-trained physicians can coordinate weight care with hormone therapy

What to weigh up

Medication starting prices exclude the $99 monthly care fee; the ongoing combined floor is $169 for compounded semaglutide and $199 for compounded tirzepatide
The first-month care discount applies once; month two returns to the full $99 fee
Weight care excludes Louisiana and Mississippi; compounded options also exclude Alabama, Arkansas, California, Nevada and DC

Compounded drugs are not FDA-approved. Understand the medication options.

Check Alloy pricing Read the full Alloy review

Rx.com

Someone who will judge it by the plan card rather than the banner, and who values no auto-renewal and a named pharmacy over the lowest sticker.

Reasons to consider it

"No automatic renewals" is printed under the plan card itself rather than buried in the terms
Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included

What to weigh up

The $99/mo semaglutide and $149/mo tirzepatide headlines require a 12-month prepayment of $1,188 or $1,788
Its program page excludes Alaska, Louisiana and Mississippi, while product pages exclude only Alaska; confirm coverage before paying
Injection only — no oral route and no brand-name lane

Compounded drugs are not FDA-approved. Understand the medication options.

Check Rx.com pricing Read the full Rx.com review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

AlloyRx.com

Normalized Cost/Month: Alloy:
71/100; Rx.com:
74/100

Price Transparency: Alloy:
78/100; Rx.com:
76/100

Nationwide Access: Alloy:
78/100; Rx.com:
82/100

Formulation Options: Alloy:
95/100; Rx.com:
62/100

Clinical Oversight: Alloy:
87/100; Rx.com:
78/100

Contract Flexibility: Alloy:
55/100; Rx.com:
96/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.