Head-to-head · Cost-Efficiency Index
PreventiveMD vs Rx.com
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
PreventiveMD
Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths.
Visit PreventiveMDRx.com
Someone who will judge it by the plan card rather than the banner, and who values no auto-renewal and a named pharmacy over the lowest sticker.
Visit Rx.comThe verdict
PreventiveMD and Rx.com tie on the Cost-Efficiency Index at 77/100, so neither wins outright on the numbers. For most shoppers we'd start with PreventiveMD (ranked #44, a hair above #45) — Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths. But Rx.com is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs PreventiveMD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | PreventiveMD | Rx.com |
|---|---|---|
| Cost-Efficiency Index | 77/100 | 77/100 |
| Semaglutide / mo | $83/mo (as low as, term not published, all-in, compounded) | $175/mo month-to-month; $165 on three months and $146 on six |
| Tirzepatide / mo | $97/mo (as low as, term not published, all-in, compounded) | $285/mo month-to-month; $265 on three months and $259 on six |
| Semaglutide / yr (modeled) | $996 | $2,100 |
| Tirzepatide / yr (modeled) | $1,164 | $3,420 |
| Coverage | 36 states | 49 states on its plan page; its own banner says all 50 |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #44 | #45 |
PreventiveMD
77/100Where the value is
- Compounded semaglutide from $83/mo and tirzepatide from $97/mo, billed as one all-in monthly price
- Brand Wegovy, Zepbound, and Foundayo (oral GLP-1) available on the same platform
- US-licensed provider reviews requests within 24 hours — no video visit required
The tradeoffs
- Both figures are 'as low as' rates and the qualifying term is not published anywhere — the checkout is gated, so whether $97 is month-to-month or a multi-month prepay cannot be established before signing up
- Brand-name routes are priced separately and do carry a fee: $49/mo membership plus medication from $149/mo for Foundayo and Wegovy, from $299/mo for Zepbound
Rx.com
77/100Where the value is
- "No automatic renewals" is printed under the plan card itself rather than buried in the terms
- Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
- One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included
The tradeoffs
- The advertised "$146/mo FOR LIFE" is a six-month prepay on semaglutide; month-to-month tirzepatide is $285
- The plan page says 49 states served while the banner on the same site says all 50
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.