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WeighLab

Zera Health vs Trillium Meds

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Zera Health

Provider comparison

Shoppers who want a named 503A pharmacy and full 50-state coverage at a moderate compounded price.

Semaglutide / month
$179/moCompounded injection, monthly billing; $149 first month or on a prepaid quarterly plan
Tirzepatide / month
$255/moCompounded injection, monthly billing; $199 first month, $215/mo on a prepaid quarterly plan
Index 79/100 · Grade CChecked October 2026

Trillium Meds

Provider comparison

Shoppers who want compounded GLP-1 in all 50 states with a real month-to-month option and a cheaper 3-month prepay.

Semaglutide / month
$159/moAll doses, compounded
Tirzepatide / month
$199/moAny dose, compounded; pharmacy-specific plans
Index 78/100 · Grade CChecked October 2026

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The comparison in brief

Zera Health has the higher Cost-Efficiency Index: 79/100 versus 78/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Zera Health

Trillium Meds

Semaglutide / month
Zera Health: $179/moCompounded injection, monthly billing; $149 first month or on a prepaid quarterly plan
Trillium Meds: $159/moAll doses, compounded
Tirzepatide / month
Zera Health: $255/moCompounded injection, monthly billing; $199 first month, $215/mo on a prepaid quarterly plan
Trillium Meds: $199/moAny dose, compounded; pharmacy-specific plans
Semaglutide / year (modeled)
Zera Health: $2,148
Trillium Meds: $1,908
Tirzepatide / year (modeled)
Zera Health: $3,060
Trillium Meds: $2,388
State availability
Zera Health: All 50 states
Trillium Meds: All 50 states
Oral / sublingual option listed
Zera Health: Yes
Trillium Meds: Not listed
Brand-name access listed
Zera Health: Not confirmed
Trillium Meds: Not confirmed
Provider facts checked
Zera Health: October 2026
Trillium Meds: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Zera Health

Shoppers who want a named 503A pharmacy and full 50-state coverage at a moderate compounded price.

Reasons to consider it

  • Named dispensing pharmacy — Strive Pharmacy, a 503A compounder — disclosed in the footer
  • LegitScript Certified badge displayed
  • States coverage across all 50 states with no exclusions listed

What to weigh up

  • First-month, monthly and quarterly prices differ; confirm your plan and second charge before paying
  • Quarterly plans require three months of payment at once
  • No individual prescriber or medical director is named

Trillium Meds

Shoppers who want compounded GLP-1 in all 50 states with a real month-to-month option and a cheaper 3-month prepay.

Reasons to consider it

  • Names pharmacy partners and displays their plan totals, formulations and shipping restrictions
  • One-month and prepaid options are published before intake
  • One-month semaglutide $159 and tirzepatide $199 offers cover any prescribed dose at several pharmacies

What to weigh up

  • Lower prepaid averages require buying multiple months at once; plans and state restrictions differ by pharmacy
  • The pharmacy card and actual fulfillment pharmacy can differ; Hyalo lists NewLife and Nova lists White Label as fulfillment partners
  • Pharmacy choice depends on availability and can be changed by the provider or pharmacy

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Zera HealthTrillium Meds
Normalized Cost/Month
Zera Health:
73/100
Trillium Meds:
80/100
Price Transparency
Zera Health:
92/100
Trillium Meds:
97/100
Nationwide Access
Zera Health:
86/100
Trillium Meds:
86/100
Formulation Options
Zera Health:
77/100
Trillium Meds:
66/100
Clinical Oversight
Zera Health:
82/100
Trillium Meds:
89/100
Contract Flexibility
Zera Health:
55/100
Trillium Meds:
25/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.