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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs Zera Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade C · #240

Zera Health

Shoppers who want a named 503A pharmacy and full 50-state coverage at a moderate compounded price.

Visit Zera Health

The verdict

Winner · CoreAge RxGrade A vs C

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 61. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Zera Health still earns a CShoppers who want a named 503A pharmacy and full 50-state coverage at a moderate compounded price.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
45

Price Transparency

97
54

Nationwide Access

98
86

Formulation Options

84
51

Clinical Oversight

90
82

Contract Flexibility

95
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxZera Health
Cost-Efficiency Index94/10061/100
Semaglutide / mo$99/moNot disclosed
Tirzepatide / mo$149/moNot disclosed
Semaglutide / yr (modeled)$1,188
Tirzepatide / yr (modeled)$1,788
CoverageAll 50 statesAll 50 states
Oral / sublingualNoYes
Brand-name accessCompounded onlyCompounded only
Rank here#1#240

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — 30 of the 381 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

Zera Health

61/100

Where the value is

  • Named dispensing pharmacy — Strive Pharmacy, a 503A compounder — disclosed in the footer
  • LegitScript Certified badge displayed
  • Stated coverage across all 50 states with no exclusions found

The tradeoffs

  • The advertised '$149' semaglutide price is explicitly a first-month-only rate; the standing price is $179/mo
  • Tirzepatide's '$199/mo' figure has no first-month/standing clarifier on the page, unlike semaglutide, so it's unclear if it will also step up after month one
Visit Zera Health

Full Zera Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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