Yes Clinic vs Avono Health

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Yes Clinic

Provider comparison

Shoppers who can pay for three months at once and want a price that won't rise as their dose goes up.

Semaglutide / month: $129/mo3-month plan, billed $387 upfront, same price at every dose, compounded
Tirzepatide / month: $149/mo3-month plan, billed $447 upfront, same price at every dose, compounded

Index 65/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Yes Clinic pricing Read review

Avono Health

Provider comparison

Readers comparing dose ranges and delivery formats who want medication, clinical review and shipping included in a published monthly price.

Semaglutide / month: $159/moMicrodose injection, compounded; standard injection $219/mo
Tirzepatide / month: $219/moMicrodose injection, compounded; standard injection $299/mo

Index 64/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Avono Health pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Yes Clinic has the higher Cost-Efficiency Index: 65/100 versus 64/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Yes Clinic: Not published
Avono Health: Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Yes Clinic

Avono Health

Semaglutide / month: Yes Clinic: $129/mo3-month plan, billed $387 upfront, same price at every dose, compounded; Avono Health: $159/moMicrodose injection, compounded; standard injection $219/mo

Tirzepatide / month: Yes Clinic: $149/mo3-month plan, billed $447 upfront, same price at every dose, compounded; Avono Health: $219/moMicrodose injection, compounded; standard injection $299/mo

Semaglutide / year (modeled): Yes Clinic: $1,548; Avono Health: $1,908

Tirzepatide / year (modeled): Yes Clinic: $1,788; Avono Health: $2,628

State availability: Yes Clinic: Not published; Avono Health: Coverage not published

Oral / sublingual option listed: Yes Clinic: Not listed; Avono Health: Yes

Brand-name access listed: Yes Clinic: Not confirmed; Avono Health: Not confirmed

Provider facts checked: Yes Clinic: October 2026; Avono Health: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Yes Clinic

Shoppers who can pay for three months at once and want a price that won't rise as their dose goes up.

Reasons to consider it

Every plan price is on the product pages with no quiz or account: semaglutide $387 for 3 months or $699 for 6, tirzepatide $447 or $894
The price stays the same at every dose, and the online consultation, shipping and membership are all included at $0
If a provider declines to prescribe, you aren't charged for medication, and a 6-month plan refunds months 4 to 6 if they aren't approved

What to weigh up

There is no single-month plan: the cheapest way in is three months paid upfront
The homepage says GLP-1 programs start "From $199/month" and mentions monthly plan rates, while the product pages show only $129 and $149 a month on 3- and 6-month plans
It doesn't name its pharmacies or its medical group, and says only that services are "not available in all states" without a list

Compounded drugs are not FDA-approved. Understand the medication options.

Check Yes Clinic pricing Read the full Yes Clinic review

Avono Health

Readers comparing dose ranges and delivery formats who want medication, clinical review and shipping included in a published monthly price.

Reasons to consider it

Publishes prices for each treatment before intake
No separate membership fee, clinician fee or shipping charge
Both GLP-1 molecules offered in injectable and oral formats

What to weigh up

Microdose prices apply to a lower-dose program and are not equivalent to standard treatment doses
Compounded oral capsules and dissolving tablets are not FDA-approved products
The dispensing pharmacy and treatment-specific state coverage list are not published

Compounded drugs are not FDA-approved. Understand the medication options.

Check Avono Health pricing Read the full Avono Health review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Yes ClinicAvono Health

Normalized Cost/Month: Yes Clinic:
76/100; Avono Health:
70/100

Price Transparency: Yes Clinic:
94/100; Avono Health:
78/100

Nationwide Access: Yes Clinic:
24/100; Avono Health:
24/100

Formulation Options: Yes Clinic:
66/100; Avono Health:
77/100

Clinical Oversight: Yes Clinic:
74/100; Avono Health:
80/100

Contract Flexibility: Yes Clinic:
43/100; Avono Health:
55/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.