Head-to-head · Cost-Efficiency Index
CoreAge Rx vs Yes Clinic
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CoreAge Rx
Anyone who wants one flat monthly price they can plan a full year around, on either molecule, without signing a contract.
Visit CoreAge RxYes Clinic
Shoppers who can pay for three months at once and want a price that won't rise as their dose goes up.
Visit Yes ClinicThe verdict
CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 65. CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee. Yes Clinic still earns a C — Shoppers who can pay for three months at once and want a price that won't rise as their dose goes up.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CoreAge Rx | Yes Clinic |
|---|---|---|
| Cost-Efficiency Index | 94/100 | 65/100 |
| Semaglutide / mo | $99/mo | $129/mo3-month plan, billed $387 upfront, same price at every dose, compounded |
| Tirzepatide / mo | $149/mo | $149/mo3-month plan, billed $447 upfront, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $1,188 | $1,548 |
| Tirzepatide / yr (modeled) | $1,788 | $1,788 |
| Coverage | All 50 states | Not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #1 | #211 |
CoreAge Rx
94/100Where the value is
- One price at every dose: semaglutide is $99 from 0.25 mg up to 2.5 mg, and tirzepatide is $149 from 2.5 mg up to 15 mg
- No membership fee, no insurance needed and no long-term contract, and the price you lock in at checkout stays put as your dose rises
- If the doctor decides a prescription isn't right for you, CoreAge refunds the medication portion of your payment
The tradeoffs
- Not the lowest price around: 35 of the 434 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
- You pay before the doctor reviews your case, and if you aren't approved the FAQ promises a 100% refund while the refund policy keeps a $50 to $100 consultation fee
Yes Clinic
65/100Where the value is
- Every plan price is on the product pages with no quiz or account: semaglutide $387 for 3 months or $699 for 6, tirzepatide $447 or $894
- The price stays the same at every dose, and the online consultation, shipping and membership are all included at $0
- If a provider declines to prescribe, you aren't charged for medication, and a 6-month plan refunds months 4 to 6 if they aren't approved
The tradeoffs
- There is no single-month plan: the cheapest way in is three months paid upfront
- The homepage says GLP-1 programs start "From $199/month" and mentions monthly plan rates, while the product pages show only $129 and $149 a month on 3- and 6-month plans
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.