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WeighLab

Wisp vs VyrarX

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

VyrarX

Provider comparison

Readers in a served state who will confirm the medication formulation, dose-specific price and refill cadence before paying.

Semaglutide / month
Formulation to confirm (semaglutide program from $179/mo)
Tirzepatide / month
Formulation to confirm (tirzepatide program from $329/mo)
Index 70/100 · Grade CChecked October 2026
Check VyrarX pricing Read review

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The comparison in brief

Both score 70/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

Wisp
39 states + DC for brand-name care; 26 states + DC for sublingual semaglutide
VyrarX
47 states; excludes California, South Carolina and New Jersey

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Wisp

VyrarX

Semaglutide / month
Wisp: $225/moCompounded oral
VyrarX: Formulation to confirm (semaglutide program from $179/mo)
Tirzepatide / month
Wisp: Not disclosed
VyrarX: Formulation to confirm (tirzepatide program from $329/mo)
Semaglutide / year (modeled)
Wisp: $2,700
VyrarX: —
Tirzepatide / year (modeled)
Wisp: —
VyrarX: —
State availability
Wisp: 39 states + DC for brand-name care; 26 states + DC for sublingual semaglutide
VyrarX: 47 states; excludes California, South Carolina and New Jersey
Oral / sublingual option listed
Wisp: Yes
VyrarX: Not listed
Brand-name access listed
Wisp: Yes
VyrarX: Not confirmed
Provider facts checked
Wisp: October 2026
VyrarX: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Wisp

Shoppers who want brand-name injectables with a sublingual semaglutide option.

Reasons to consider it

  • Broad GLP-1 menu — branded injectables (Wegovy, Zepbound, Saxenda) plus a compounded sublingual option
  • LegitScript certified with named board-certified providers (Dr. Shannon Chatham DO, Andrea Sleeth WHNP-BC)
  • Unusually candid about the sublingual option's limits, noting effectiveness in patients may vary

What to weigh up

  • The $99 Weight Care Consult is a care charge, not a Zepbound price; no monthly billing period is stated, and the medication is paid for separately at your pharmacy
  • The compounded semaglutide is sublingual drops; Wisp says this formulation has not been tested in the human body, so effectiveness in patients may vary
  • Brand-name access is a prescription, not a dispensed product, so the drug cost is outside anything quoted here

Compounded drugs are not FDA-approved. Understand the medication options.

Check Wisp pricing Read the full Wisp review

VyrarX

Readers in a served state who will confirm the medication formulation, dose-specific price and refill cadence before paying.

Reasons to consider it

  • Publishes starting program rates for both molecules
  • Names Locum Tele as its provider network and Rush Pharmacy as its pharmacy
  • Lists the three excluded states in its terms

What to weigh up

  • The public program cards do not identify the medication as compounded or branded; confirm the exact product
  • Higher-dose prices, the shipment supply length and renewal cadence are not published
  • No individual medical director is named
Check VyrarX pricing Read the full VyrarX review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

WispVyrarX
Normalized Cost/Month
Wisp:
58/100
VyrarX:
45/100
Price Transparency
Wisp:
86/100
VyrarX:
92/100
Nationwide Access
Wisp:
66/100
VyrarX:
78/100
Formulation Options
Wisp:
77/100
VyrarX:
66/100
Clinical Oversight
Wisp:
82/100
VyrarX:
90/100
Contract Flexibility
Wisp:
55/100
VyrarX:
49/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.