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WeighLab

TRT Nation vs RxPepsDirect

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

TRT Nation

Provider comparison

Patients comfortable with a three-month purchase and separately arranged labs.

Semaglutide / month
Not disclosed
Tirzepatide / month
$219/moEquivalent (compounded; $657 minimum purchase for 3 months)
Index 61/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check TRT Nation pricing Read review

RxPepsDirect

Provider comparison

Cost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.

Semaglutide / month
$79/moStarting dose, visit fee and shipping included, compounded
Tirzepatide / month
$99/moStarting dose, visit fee and shipping included, compounded
Index 60/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check RxPepsDirect pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

TRT Nation has the higher Cost-Efficiency Index: 61/100 versus 60/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

TRT Nation
44 states
RxPepsDirect
28 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

TRT Nation

RxPepsDirect

Semaglutide / month
TRT Nation: Not disclosed
RxPepsDirect: $79/moStarting dose, visit fee and shipping included, compounded
Tirzepatide / month
TRT Nation: $219/moEquivalent (compounded; $657 minimum purchase for 3 months)
RxPepsDirect: $99/moStarting dose, visit fee and shipping included, compounded
Semaglutide / year (modeled)
TRT Nation: —
RxPepsDirect: $948
Tirzepatide / year (modeled)
TRT Nation: $2,628
RxPepsDirect: $1,188
State availability
TRT Nation: 44 states
RxPepsDirect: 28 states
Oral / sublingual option listed
TRT Nation: Not listed
RxPepsDirect: Not listed
Brand-name access listed
TRT Nation: Not confirmed
RxPepsDirect: Not confirmed
Provider facts checked
TRT Nation: October 2026
RxPepsDirect: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

TRT Nation

Patients comfortable with a three-month purchase and separately arranged labs.

Reasons to consider it

  • Flat tirzepatide price across doses
  • Public minimum purchase term
  • Online provider consultations

What to weigh up

  • At least $657 for the initial three-month purchase before discounts
  • Labs cost extra unless qualifying outside results are provided
  • No pharmacy is named

Compounded drugs are not FDA-approved. Understand the medication options.

Check TRT Nation pricing Read the full TRT Nation review

RxPepsDirect

Cost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.

Reasons to consider it

  • Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
  • No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
  • Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas State Board of Pharmacy license #34829

What to weigh up

  • The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
  • The figure above is the starter vial; the published dose ladder climbs month by month, to $108.64 for a month-six semaglutide vial before the visit charge and shipping
  • Minimal clinical oversight: a roughly two-minute asynchronous intake, no live video consult, no labs required and no published dose-escalation monitoring

Compounded drugs are not FDA-approved. Understand the medication options.

Check RxPepsDirect pricing Read the full RxPepsDirect review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

TRT NationRxPepsDirect
Normalized Cost/Month
TRT Nation:
43/100
RxPepsDirect:
83/100
Price Transparency
TRT Nation:
94/100
RxPepsDirect:
30/100
Nationwide Access
TRT Nation:
66/100
RxPepsDirect:
52/100
Formulation Options
TRT Nation:
53/100
RxPepsDirect:
66/100
Clinical Oversight
TRT Nation:
82/100
RxPepsDirect:
70/100
Contract Flexibility
TRT Nation:
21/100
RxPepsDirect:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.