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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs RxPepsDirect

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade C · #243

RxPepsDirect

Cost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.

Visit RxPepsDirect

The verdict

Winner · CoreAge RxGrade A vs C

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 60. Best value on the board: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. RxPepsDirect still earns a CCost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
83

Price Transparency

97
30

Nationwide Access

98
52

Formulation Options

84
66

Clinical Oversight

90
70

Contract Flexibility

95
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxRxPepsDirect
Cost-Efficiency Index94/10060/100
Semaglutide / mo$149/mo$79/mo (starting dose, visit fee and shipping included, compounded)
Tirzepatide / mo$349/mo$99/mo (starting dose, visit fee and shipping included, compounded)
Semaglutide / yr (modeled)$1,788$948
Tirzepatide / yr (modeled)$4,188$1,188
CoverageAll 50 states28 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank on the board#1#243

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — cheaper teaser tiers exist (Direct GLP lists $65, Ondra $93 on semaglutide)
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

RxPepsDirect

60/100

Where the value is

  • Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
  • No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
  • Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas Board #34829

The tradeoffs

  • The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
  • Higher doses need more than one vial a month and the site publishes no price for the dose you titrate up to, so the figure above is a floor
Visit RxPepsDirect

Full RxPepsDirect review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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