Synergy Rx vs He & She MD

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Synergy Rx

Provider comparison

Readers comparing injection, dissolving-tablet and brand-name routes who will confirm the plan total and billing schedule.

Semaglutide / month: $199Starting price (compounded injection; billing cycle and dose not stated)
Tirzepatide / month: $349Starting price (compounded injection; billing cycle and dose not stated)

Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Synergy Rx pricing Read review

He & She MD

Provider comparison

Readers comparing monthly treatment against prepaid terms who will resolve conflicting product-page prices before paying.

Semaglutide / month: $199/moMonth to month, compounded; every lower rate is a prepaid term
Tirzepatide / month: $299/moMonth to month, compounded; every lower rate is a prepaid term

Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check He & She MD pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 79/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

Synergy Rx: All 50 states claimed in FAQ; subject to provider availability
He & She MD: 49 states, excluding Louisiana (GLP-1)

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Synergy Rx

He & She MD

Semaglutide / month: Synergy Rx: $199Starting price (compounded injection; billing cycle and dose not stated); He & She MD: $199/moMonth to month, compounded; every lower rate is a prepaid term

Tirzepatide / month: Synergy Rx: $349Starting price (compounded injection; billing cycle and dose not stated); He & She MD: $299/moMonth to month, compounded; every lower rate is a prepaid term

Semaglutide / year (modeled): Synergy Rx: $2,388; He & She MD: $2,388

Tirzepatide / year (modeled): Synergy Rx: $4,188; He & She MD: $3,588

State availability: Synergy Rx: All 50 states claimed in FAQ; subject to provider availability; He & She MD: 49 states, excluding Louisiana (GLP-1)

Oral / sublingual option listed: Synergy Rx: Yes; He & She MD: Yes

Brand-name access listed: Synergy Rx: Yes; He & She MD: Yes

Provider facts checked: Synergy Rx: October 2026; He & She MD: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Synergy Rx

Readers comparing injection, dissolving-tablet and brand-name routes who will confirm the plan total and billing schedule.

Reasons to consider it

Offers compounded injections, compounded oral dissolving tablets and brand-name Wegovy, Mounjaro and Ozempic
Lists starting prices before consultation
FAQ says all 50 states, subject to state rules and licensed-provider availability

What to weigh up

Starting figures do not specify the billing cycle or dose; confirm the complete plan total
Oral semaglutide starts at $299 and oral tirzepatide at $399, above the injection floors
State availability is conditional; confirm that a licensed provider can treat you

Compounded drugs are not FDA-approved. Understand the medication options.

Check Synergy Rx pricing Read the full Synergy Rx review

He & She MD

Readers comparing monthly treatment against prepaid terms who will resolve conflicting product-page prices before paying.

Reasons to consider it

Offers compounded semaglutide and tirzepatide injections and oral options, plus branded GLP-1 prescribing
Names Dr. Ozita Cooper as CMO, Wasef Health as the provider group, and two dispensing partners: Jungle Jim's Pharmacy and GoGoMeds
Publishes monthly, quarterly, six-month and annual plans

What to weigh up

The plans page lists $199 semaglutide and $299 tirzepatide monthly, but the individual injection pages list $249 and $339 for one month; confirm the actual bill
Quarterly, six-month and annual prices require the whole term paid upfront; six-month promotional terms may renew higher
The FAQ says Jungle Jim's cannot dispense sterile compounds and lists state exclusions; ask which partner fills your injectable prescription

Compounded drugs are not FDA-approved. Understand the medication options.

Check He & She MD pricing Read the full He & She MD review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Synergy RxHe & She MD

Normalized Cost/Month: Synergy Rx:
74/100; He & She MD:
78/100

Price Transparency: Synergy Rx:
65/100; He & She MD:
97/100

Nationwide Access: Synergy Rx:
88/100; He & She MD:
78/100

Formulation Options: Synergy Rx:
95/100; He & She MD:
90/100

Clinical Oversight: Synergy Rx:
90/100; He & She MD:
85/100

Contract Flexibility: Synergy Rx:
68/100; He & She MD:
31/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

Alternatives to Synergy Rx Alternatives to He & She MD

More provider matchups

CoreAge Rx vs Synergy Rx CoreAge Rx vs He & She MD

Choose a different comparison

Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.