Head-to-head · Cost-Efficiency Index
SkyRx vs The Virtual NP
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
SkyRx
Shoppers willing to commit and prepay a full year upfront in exchange for a lower blended monthly rate.
Visit SkyRxThe Virtual NP
Patients in its 6 served states who specifically want branded (not compounded) Wegovy/Zepbound with a low, flat provider fee.
Visit The Virtual NPThe verdict
SkyRx and The Virtual NP tie on the Cost-Efficiency Index at 55/100, so neither wins outright on the numbers. For most shoppers we'd start with SkyRx (ranked #346, a hair above #350) — Shoppers willing to commit and prepay a full year upfront in exchange for a lower blended monthly rate. But The Virtual NP is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs SkyRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | SkyRx | The Virtual NP |
|---|---|---|
| Cost-Efficiency Index | 55/100 | 55/100 |
| Semaglutide / mo | $199/mo (compounded) | Not disclosed |
| Tirzepatide / mo | Not disclosed | Not disclosed |
| Semaglutide / yr (modeled) | $2,388 | — |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | Coverage not published | 7 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #346 | #350 |
SkyRx
55/100Where the value is
- Simple, single headline price displayed on the weight-loss page
- Claims LegitScript certification
- Straightforward telehealth intake flow
The tradeoffs
- The '$199/mo' price is a 12-month prepay rate, not a cancel-anytime monthly price -- a major disclosure trap
- Tirzepatide not yet available ('coming soon'), so half the category is unpriced
The Virtual NP
55/100Where the value is
- Prescribes FDA-approved branded medications (Wegovy/Zepbound) rather than compounded versions
- Named clinical founder (Sandra Jordan, MSN, APRN, FNP-C)
- Low, transparent provider fee ($99/visit or $75/month membership)
The tradeoffs
- No all-in monthly cost available -- medication price is separate and varies by pharmacy/insurance
- Narrow 6-state footprint (FL, NY, AZ, NV, NM, KS)
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.