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WeighLab

SkinnyRx vs WeightlessRx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

SkinnyRx

Affiliate partner

Shoppers who want a cheap first month to see how they tolerate a GLP-1, and who will budget for the price from month two.

Semaglutide / month
$249/moMonth to month after a $99 first month ($199/mo on a 12-month plan)
Tirzepatide / month
$299/moMonth to month after a $99 first month ($225/mo on a 12-month plan)
Index 74/100 · Grade CChecked October 2026

WeightlessRx

Provider comparison

Shoppers comfortable buying a three-month supply who want medication, clinician messaging, nutrition support, and supplies included.

Semaglutide / month
$167/moAll doses, $500 total for 3 months prepaid, compounded
Tirzepatide / month
$233/moAll doses, $700 total for 3 months prepaid, compounded
Index 76/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

WeightlessRx has the higher Cost-Efficiency Index: 76/100 versus 74/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

SkinnyRx
Most states
WeightlessRx
All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

SkinnyRx

WeightlessRx

Semaglutide / month
SkinnyRx: $249/moMonth to month after a $99 first month ($199/mo on a 12-month plan)
WeightlessRx: $167/moAll doses, $500 total for 3 months prepaid, compounded
Tirzepatide / month
SkinnyRx: $299/moMonth to month after a $99 first month ($225/mo on a 12-month plan)
WeightlessRx: $233/moAll doses, $700 total for 3 months prepaid, compounded
Semaglutide / year (modeled)
SkinnyRx: $2,988
WeightlessRx: $2,004
Tirzepatide / year (modeled)
SkinnyRx: $3,588
WeightlessRx: $2,796
State availability
SkinnyRx: Most states
WeightlessRx: All 50 states
Oral / sublingual option listed
SkinnyRx: Yes
WeightlessRx: Not listed
Brand-name access listed
SkinnyRx: Not confirmed
WeightlessRx: Not confirmed
Provider facts checked
SkinnyRx: October 2026
WeightlessRx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

SkinnyRx

Shoppers who want a cheap first month to see how they tolerate a GLP-1, and who will budget for the price from month two.

Reasons to consider it

  • The first month of either injection is $99, so trying the medication costs little
  • Prepaid plans lower the price: semaglutide renews at $225 a month on four months, $215 on six and $199 on twelve
  • Both compounded molecules come as a weekly injection or a daily tablet

What to weigh up

  • From month two the injection is $249 for semaglutide or $299 for tirzepatide, well above the $99 you see first
  • An FDA warning letter is on public record against Lean Rx, Inc. dba SkinnyRx, issued February 2026
  • Brand-name drugs appear in its catalog, but the Wegovy pill is listed as unavailable

Regulatory note: the FDA issued a warning letter to Lean Rx, Inc. dba SkinnyRx in February 2026. We still list and link to SkinnyRx; you should know the letter is on the public record before you decide.

WeightlessRx

Shoppers comfortable buying a three-month supply who want medication, clinician messaging, nutrition support, and supplies included.

Reasons to consider it

  • Published three-month totals of $500 for semaglutide and $700 for tirzepatide include every prescribed dose
  • No separate membership or consultation fee; supplies, required labs and shipping included
  • Names VitaScripts Pharmacy and displays a LegitScript certification claim

What to weigh up

  • The displayed monthly figures are averages for a prepaid three-month supply, not a published month-to-month bill
  • The banner offers monthly or three-month plans, but the FAQ says every plan is a three-month supply; confirm your billing term
  • Cancellation needs at least five business days notice to stop the next charge

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

SkinnyRxWeightlessRx
Normalized Cost/Month
SkinnyRx:
71/100
WeightlessRx:
66/100
Price Transparency
SkinnyRx:
84/100
WeightlessRx:
97/100
Nationwide Access
SkinnyRx:
82/100
WeightlessRx:
86/100
Formulation Options
SkinnyRx:
73/100
WeightlessRx:
66/100
Clinical Oversight
SkinnyRx:
66/100
WeightlessRx:
86/100
Contract Flexibility
SkinnyRx:
58/100
WeightlessRx:
43/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.