Best-value alternatives
Alternatives to SkinnyRx
SkinnyRx scores 71/100 on our Cost-Efficiency Index (ranked #60 of 529). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C71/ 100Index
He & She MD
Ranked #59He & She MD is a nationwide telehealth weight-loss clinic offering compounded semaglutide and tirzepatide (injectable, oral, or microdose) plus brand-name access.
- Sema
- $199/mo (month to month, compounded; every lower rate is a prepaid term)
- Tirz
- $299/mo (month to month, compounded; every lower rate is a prepaid term)
- Coverage
- Multi-state
- Brand
- Yes
- 03C71/ 100Index
Direct Meds
Ranked #58The widest set of routes in this ranking — sublingual and injection on both semaglutide and tirzepatide, every SKU priced in the open — sold well above the median, on a plan that only ever bills against a 90-day supply.
- Sema
- $249/mo (sublingual, 90-day supply billed monthly)
- Tirz
- $299/mo (sublingual, 90-day supply billed monthly)
- Coverage
- Not disclosed
- Brand
- Compounded
Regulatory note: the FDA issued a warning letter to directmeds.com, Inc. dba DirectMeds in September 2025. We still list and link to Direct Meds; you should know the letter is on the public record before you decide.
- 04C71/ 100Index
Gala Health
Ranked #57Every dose at one published price, with the whole price list visible before you hand over an email — but the only terms it sells on are a yearly subscription at $179 or a three-month plan at $199, so there is no monthly number here to compare with anyone else's.
- Sema
- No compounded option — brand Ozempic only, $1,299/mo
- Tirz
- $179/mo (yearly subscription; $199/mo on a 3-month plan)
- Coverage
- Multi-state
- Brand
- Yes
- 05C74/ 100Index
NextMeds
Ranked #56NextMeds is a compounded-GLP-1 telehealth platform naming a real clinical group (Lion MD, led by two NPI-verifiable physicians) and six named compounding pharmacies — unusually transparent on that front.
- Sema
- $79/mo (starting dose, promotional rate, compounded)
- Tirz
- $129/mo (starting dose, promotional rate, compounded)
- Coverage
- All 50 states
- Brand
- Compounded
- 06C74/ 100Index
Nalena
Ranked #55Nalena is a women-focused, GLP-1-only telehealth platform offering compounded semaglutide and tirzepatide with medication included — no separate membership or visit fees.
- Sema
- $149/mo (starting dose, compounded)
- Tirz
- $149/mo (starting dose, compounded)
- Coverage
- All 50 states
- Brand
- Compounded
- 07C74/ 100Index
Jyra Health
Ranked #54Jyra Health is a compounded GLP-1 telehealth clinic charging $175/mo (semaglutide) or $199/mo (tirzepatide) month-to-month, discounted to $139/mo and $179/mo respectively on a 3-month prepaid plan.
- Sema
- $175/mo (all doses, compounded)
- Tirz
- $199/mo (all doses, compounded)
- Coverage
- All 50 states
- Brand
- Compounded
- 08C74/ 100Index
DoctorAdam
Ranked #53DoctorAdam is a Shopify-storefront telehealth company selling compounded oral (sublingual) and injectable semaglutide and tirzepatide plus NAD+/glutathione add-ons, prescribed by a named roster of six MD/NP prescribers.
- Sema
- $129/mo (starting dose, compounded oral)
- Tirz
- $199/mo (starting dose, compounded oral)
- Coverage
- 44 states
- Brand
- Compounded
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.