Skip to content
WeighLab

SkinnyRx vs Unique Physique

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

SkinnyRx

Affiliate partner

Shoppers who want a cheap first month to see how they tolerate a GLP-1, and who will budget for the price from month two.

Semaglutide / month
$249/moMonth to month after a $99 first month ($199/mo on a 12-month plan)
Tirzepatide / month
$299/moMonth to month after a $99 first month ($225/mo on a 12-month plan)
Index 74/100 · Grade CChecked October 2026

Unique Physique

Provider comparison

Shoppers comfortable inferring which drug they're buying from a dose ceiling rather than a named label.

Semaglutide / month
$159/moAll doses, compounded
Tirzepatide / month
$289/moAll doses, compounded
Index 76/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Unique Physique has the higher Cost-Efficiency Index: 76/100 versus 74/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

SkinnyRx
Most states
Unique Physique
46 states (not AK, CA, KS or WI)

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

SkinnyRx

Unique Physique

Semaglutide / month
SkinnyRx: $249/moMonth to month after a $99 first month ($199/mo on a 12-month plan)
Unique Physique: $159/moAll doses, compounded
Tirzepatide / month
SkinnyRx: $299/moMonth to month after a $99 first month ($225/mo on a 12-month plan)
Unique Physique: $289/moAll doses, compounded
Semaglutide / year (modeled)
SkinnyRx: $2,988
Unique Physique: $1,908
Tirzepatide / year (modeled)
SkinnyRx: $3,588
Unique Physique: $3,468
State availability
SkinnyRx: Most states
Unique Physique: 46 states (not AK, CA, KS or WI)
Oral / sublingual option listed
SkinnyRx: Yes
Unique Physique: Not listed
Brand-name access listed
SkinnyRx: Not confirmed
Unique Physique: Not confirmed
Provider facts checked
SkinnyRx: October 2026
Unique Physique: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

SkinnyRx

Shoppers who want a cheap first month to see how they tolerate a GLP-1, and who will budget for the price from month two.

Reasons to consider it

  • The first month of either injection is $99, so trying the medication costs little
  • Prepaid plans lower the price: semaglutide renews at $225 a month on four months, $215 on six and $199 on twelve
  • Both compounded molecules come as a weekly injection or a daily tablet

What to weigh up

  • From month two the injection is $249 for semaglutide or $299 for tirzepatide, well above the $99 you see first
  • An FDA warning letter is on public record against Lean Rx, Inc. dba SkinnyRx, issued February 2026
  • Brand-name drugs appear in its catalog, but the Wegovy pill is listed as unavailable

Regulatory note: the FDA issued a warning letter to Lean Rx, Inc. dba SkinnyRx in February 2026. We still list and link to SkinnyRx; you should know the letter is on the public record before you decide.

Unique Physique

Shoppers comfortable inferring which drug they're buying from a dose ceiling rather than a named label.

Reasons to consider it

  • No-contract, single flat monthly price at each tier rather than a shifting per-dose ladder
  • Named Medical Director with a real, checkable credential: Reena John, DO
  • States it provides consultations via 'Licensed Clinicians in the Patient's State,' implying state-matched prescribers

What to weigh up

  • The pricing page never explicitly names semaglutide or tirzepatide — which drug each tier covers is inferred from the dose ceiling, not stated by the company
  • No compounding pharmacy is named anywhere reached, unusual for a compounded-GLP-1 provider
  • Not available in Alaska, California, Kansas or Wisconsin

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

SkinnyRxUnique Physique
Normalized Cost/Month
SkinnyRx:
71/100
Unique Physique:
80/100
Price Transparency
SkinnyRx:
84/100
Unique Physique:
94/100
Nationwide Access
SkinnyRx:
82/100
Unique Physique:
78/100
Formulation Options
SkinnyRx:
73/100
Unique Physique:
66/100
Clinical Oversight
SkinnyRx:
66/100
Unique Physique:
67/100
Contract Flexibility
SkinnyRx:
58/100
Unique Physique:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

More provider matchups
Choose a different comparison

Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.