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WeighLab

Rylo Health vs Sprout Health

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Rylo Health

Provider comparison

Shoppers who want one flat all-in monthly rate that doesn't rise as the dose increases.

Semaglutide / month
$139/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded
Tirzepatide / month
$229/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded
Index 84/100 · Grade BChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Rylo Health pricing Read review

Sprout Health

Affiliate partner

Price-conscious shoppers who want a quick online intake and don't mind a subscription that bills every four weeks.

Semaglutide / month
$149 per 4 weeks$99/mo on a prepaid 12-month plan
Tirzepatide / month
$199 per 4 weeks$149/mo on a prepaid 12-month plan
Index 80/100 · Grade B−Checked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Sprout Health pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Rylo Health has the higher Cost-Efficiency Index: 84/100 versus 80/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Rylo Health
All 50 states
Sprout Health
44 states (not AL, AR, CA, LA, MS or ND)

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Rylo Health

Sprout Health

Semaglutide / month
Rylo Health: $139/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded
Sprout Health: $149 per 4 weeks$99/mo on a prepaid 12-month plan
Tirzepatide / month
Rylo Health: $229/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded
Sprout Health: $199 per 4 weeks$149/mo on a prepaid 12-month plan
Semaglutide / year (modeled)
Rylo Health: $1,668
Sprout Health: $1,93713 charges
Tirzepatide / year (modeled)
Rylo Health: $2,748
Sprout Health: $2,58713 charges
State availability
Rylo Health: All 50 states
Sprout Health: 44 states (not AL, AR, CA, LA, MS or ND)
Oral / sublingual option listed
Rylo Health: Not listed
Sprout Health: Not listed
Brand-name access listed
Rylo Health: Not confirmed
Sprout Health: Not confirmed
Provider facts checked
Rylo Health: October 2026
Sprout Health: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Rylo Health

Shoppers who want one flat all-in monthly rate that doesn't rise as the dose increases.

Reasons to consider it

  • Stated flat pricing regardless of dose — 'No surprise charges, no tiered pricing' — a genuine differentiator versus tiered competitors
  • Medication, provider review and shipping are all stated as included in the quoted price, with no add-ons listed
  • Names its physician group (Lone Star Virtual Health PLLC) and dispensing pharmacy (VialsRX, Houston TX) rather than leaving both anonymous

What to weigh up

  • The advertised $100/$160 monthly equivalents require $299/$479 paid once per quarter
  • Its product pages say no membership fees, while the terms describe separately billed membership; confirm the complete charge
  • The terms say refunds depend on the treatment stage and describe the full terms as still being finalized

Compounded drugs are not FDA-approved. Understand the medication options.

Check Rylo Health pricing Read the full Rylo Health review

Sprout Health

Price-conscious shoppers who want a quick online intake and don't mind a subscription that bills every four weeks.

Reasons to consider it

  • Prices are on the homepage before you start: $149 or $199 every four weeks, or $1,188 and $1,788 for a prepaid year
  • A licensed clinician reviews your intake, and most prescriptions reach the pharmacy within two business days
  • Sprout names its dispensing pharmacies, Foothills Pharmacy and Promise Pharmacy, in its terms

What to weigh up

  • Billing runs every four weeks, so the monthly plan is 13 charges a year, about $1,937 on semaglutide and $2,587 on tirzepatide
  • Cancel after a provider has reviewed your case and you lose a $50 review fee; once the prescription reaches the pharmacy, nothing is refunded
  • To avoid the next charge you must cancel at least 48 hours before the billing date

Regulatory note: the FDA issued a warning letter to Sprout Health Partners LLC dba Sprout Health in September 2025. We still list and link to Sprout Health; you should know the letter is on the public record before you decide.

Compounded drugs are not FDA-approved. Understand the medication options.

Check Sprout Health pricing Read the full Sprout Health review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Rylo HealthSprout Health
Normalized Cost/Month
Rylo Health:
87/100
Sprout Health:
87/100
Price Transparency
Rylo Health:
94/100
Sprout Health:
84/100
Nationwide Access
Rylo Health:
86/100
Sprout Health:
66/100
Formulation Options
Rylo Health:
66/100
Sprout Health:
69/100
Clinical Oversight
Rylo Health:
83/100
Sprout Health:
82/100
Contract Flexibility
Rylo Health:
83/100
Sprout Health:
88/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.