Alternatives
Alternatives to Rylo Health
Rylo Health scores 84/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.
Rylo Health at a glance
- Semaglutide
- $139/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded
- Tirzepatide
- $229/moAll doses, monthly plan; lower rates with quarterly prepayment, compounded
- Coverage
- All 50 states
- Brand-name GLP-1s
- No, compounded only
- Oral option
- No
- Pricing verified
- October 2026
3 of the 8 programs below list semaglutide for less than Rylo Health's $139 a month. 3 of the 8 list tirzepatide for less than its $229 a month.
Rylo Health offers compounded semaglutide and tirzepatide with physician review, supplies and shipping included, at a monthly or prepaid quarterly price.
Best for: Shoppers who want one flat all-in monthly rate that doesn't rise as the dose increases.
What Rylo Health does well
- Stated flat pricing regardless of dose — 'No surprise charges, no tiered pricing' — a genuine differentiator versus tiered competitors
- Medication, provider review and shipping are all stated as included in the quoted price, with no add-ons listed
- Names its physician group (Lone Star Virtual Health PLLC) and dispensing pharmacy (VialsRX, Houston TX) rather than leaving both anonymous
- HSA/FSA accepted per the site
- LegitScript badge displayed
Why readers look for an alternative
- The advertised $100/$160 monthly equivalents require $299/$479 paid once per quarter
- Its product pages say no membership fees, while the terms describe separately billed membership; confirm the complete charge
- The terms say refunds depend on the treatment stage and describe the full terms as still being finalized
- Partner01A94/ 100Index
CoreAge Rx
CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rylo Health: $40/mo less for semaglutide · $80/mo less for tirzepatide
- 02B86/ 100Index
Breeze Meds
All-50-state compounded GLP-1 from a program that names its NPI-verifiable physicians and its dispensing pharmacies and carries LegitScript certification, so you can check who writes and fills your prescription.
- Sema
- $199/mo
- Tirz
- $399/moOn the product grid; the post-intake screen shows $299 — Breeze publishes both
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rylo Health: $60/mo more for semaglutide · $170/mo more for tirzepatide · offers an oral option
- 03B86/ 100Index
Kongo
$119 semaglutide nationwide from a LegitScript-verified pharmacy — a genuinely cheap all-50 entry point, though the $229 tirzepatide pulls the combined value back to mid-pack.
- Sema
- $119/mo
- Tirz
- $229/mo
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rylo Health: $20/mo less for semaglutide
- 04B85/ 100Index
PepHaūs
Mid-market $152/$246 pricing on both molecules, all-50 and LegitScript-verified — a clean, verified nationwide option that trades rock-bottom cost for a dependable pharmacy.
- Sema
- $152/mo
- Tirz
- $246/mo
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rylo Health: $13/mo more for semaglutide · $17/mo more for tirzepatide
- 05B85/ 100Index
Polly
Polly, formerly Piper, sells compounded semaglutide at $179 a month and tirzepatide at $279 month to month, all-inclusive and the same at every dose, with lower rates on prepaid three- and six-month plans.
- Sema
- $179/moMonth-to-month, same price at every dose ($166/mo on a 3-month plan, $135/mo on a 6-month plan, each paid up front)
- Tirz
- $279/moMonth-to-month, same price at every dose ($216/mo on a 3-month plan, $199/mo on a 6-month plan, $1,194 paid up front)
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rylo Health: $40/mo more for semaglutide · $50/mo more for tirzepatide
- 06B85/ 100Index
Pallas Health
Prices both molecules openly at one rate for every dose, billed every 4 weeks, and also sells brand-name Wegovy, Zepbound, Ozempic, Mounjaro, the Wegovy pill and Foundayo cash-pay, in all 50 states and D.C.
- Sema
- $199Every 4 weeks (same price at every dose, compounded, care included; first month $139; $139/mo average on the annual plan)
- Tirz
- $299Every 4 weeks (same price at every dose, compounded, care included; first month $179; $239/mo average on the annual plan)
- Coverage
- All 50 states + DC
- Brand
- Yes
Compared with Rylo Health: $60/mo more for semaglutide · $70/mo more for tirzepatide · also lists brand-name GLP-1s · offers an oral option
- 07B85/ 100Index
Renlo Health
Renlo Health publishes flat monthly compounded semaglutide at $149 and tirzepatide at $199, with named clinical leadership, a named pharmacy and nationwide evaluation access.
- Sema
- $149/moBilled monthly at every dose
- Tirz
- $199/moBilled monthly at every dose
- Coverage
- Multi-state
- Brand
- Compounded
Compared with Rylo Health: $10/mo more for semaglutide · $30/mo less for tirzepatide
- 08B84/ 100Index
FMmeds
FMmeds is a compounded-GLP-1 telehealth membership selling semaglutide from $95/mo and tirzepatide from $145/mo, both co-formulated with Vitamin B12 and dispensed by Manifest Pharmacy.
- Sema
- $95/moAll doses, physician review and medication included, compounded
- Tirz
- $145/moAll doses, physician review and medication included, compounded
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rylo Health: $44/mo less for semaglutide · $84/mo less for tirzepatide
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.