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WeighLab

Rex MD vs Wisp

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Rex MD

Provider comparison

Patients seeking a Wegovy pill plan with medication and provider care in one monthly price.

Semaglutide / month
$349/moBrand Wegovy pill, all titration doses; provider care included
Tirzepatide / month
$424/moBrand Zepbound, plus a separate fee
Index 71/100 · Grade CChecked October 2026
Check Rex MD pricing Read review

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The comparison in brief

Rex MD has the higher Cost-Efficiency Index: 71/100 versus 70/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Rex MD
All 50 states
Wisp
39 states + DC for brand-name care; 26 states + DC for sublingual semaglutide

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Rex MD

Wisp

Semaglutide / month
Rex MD: $349/moBrand Wegovy pill, all titration doses; provider care included
Wisp: $225/moCompounded oral
Tirzepatide / month
Rex MD: $424/moBrand Zepbound, plus a separate fee
Wisp: Not disclosed
Semaglutide / year (modeled)
Rex MD: $4,188
Wisp: $2,700
Tirzepatide / year (modeled)
Rex MD: $5,088
Wisp: —
State availability
Rex MD: All 50 states
Wisp: 39 states + DC for brand-name care; 26 states + DC for sublingual semaglutide
Oral / sublingual option listed
Rex MD: Yes
Wisp: Yes
Brand-name access listed
Rex MD: Yes
Wisp: Yes
Provider facts checked
Rex MD: October 2026
Wisp: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Rex MD

Patients seeking a Wegovy pill plan with medication and provider care in one monthly price.

Reasons to consider it

  • Wegovy pill plan includes medication and provider care for $349 monthly
  • The pill price is locked across listed titration doses
  • Names Dr. Anthony Puopolo and the Rex MD Affiliated Medical Group

What to weigh up

  • The $349 pill plan differs from the injection route with separate program and manufacturer charges
  • Zepbound pricing depends on the prescribed dose and manufacturer terms
  • The weight program does not accept insurance
Check Rex MD pricing Read the full Rex MD review

Wisp

Shoppers who want brand-name injectables with a sublingual semaglutide option.

Reasons to consider it

  • Broad GLP-1 menu — branded injectables (Wegovy, Zepbound, Saxenda) plus a compounded sublingual option
  • LegitScript certified with named board-certified providers (Dr. Shannon Chatham DO, Andrea Sleeth WHNP-BC)
  • Unusually candid about the sublingual option's limits, noting effectiveness in patients may vary

What to weigh up

  • The $99 Weight Care Consult is a care charge, not a Zepbound price; no monthly billing period is stated, and the medication is paid for separately at your pharmacy
  • The compounded semaglutide is sublingual drops; Wisp says this formulation has not been tested in the human body, so effectiveness in patients may vary
  • Brand-name access is a prescription, not a dispensed product, so the drug cost is outside anything quoted here

Compounded drugs are not FDA-approved. Understand the medication options.

Check Wisp pricing Read the full Wisp review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Rex MDWisp
Normalized Cost/Month
Rex MD:
41/100
Wisp:
58/100
Price Transparency
Rex MD:
78/100
Wisp:
86/100
Nationwide Access
Rex MD:
86/100
Wisp:
66/100
Formulation Options
Rex MD:
90/100
Wisp:
77/100
Clinical Oversight
Rex MD:
89/100
Wisp:
82/100
Contract Flexibility
Rex MD:
55/100
Wisp:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.