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WeighLab

PlexusDx vs Zera Health

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

PlexusDx

Provider comparison

Shoppers who want one price at every dose, an oral option for either molecule, and all 50 states.

Semaglutide / month
$189/moSame price at every dose, month to month, compounded, all-inclusive; $169/mo on a 3-month plan, $149/mo on a 6-month plan
Tirzepatide / month
$289/moSame price at every dose, month to month, compounded, all-inclusive; $269/mo on a 3-month plan, $249/mo on a 6-month plan
Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check PlexusDx pricing Read review

Zera Health

Provider comparison

Shoppers who want a named 503A pharmacy and full 50-state coverage at a moderate compounded price.

Semaglutide / month
$179/moCompounded injection, monthly billing; $149 first month or on a prepaid quarterly plan
Tirzepatide / month
$255/moCompounded injection, monthly billing; $199 first month, $215/mo on a prepaid quarterly plan
Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Zera Health pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 79/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

PlexusDx

Zera Health

Semaglutide / month
PlexusDx: $189/moSame price at every dose, month to month, compounded, all-inclusive; $169/mo on a 3-month plan, $149/mo on a 6-month plan
Zera Health: $179/moCompounded injection, monthly billing; $149 first month or on a prepaid quarterly plan
Tirzepatide / month
PlexusDx: $289/moSame price at every dose, month to month, compounded, all-inclusive; $269/mo on a 3-month plan, $249/mo on a 6-month plan
Zera Health: $255/moCompounded injection, monthly billing; $199 first month, $215/mo on a prepaid quarterly plan
Semaglutide / year (modeled)
PlexusDx: $2,268
Zera Health: $2,148
Tirzepatide / year (modeled)
PlexusDx: $3,468
Zera Health: $3,060
State availability
PlexusDx: All 50 states
Zera Health: All 50 states
Oral / sublingual option listed
PlexusDx: Yes
Zera Health: Yes
Brand-name access listed
PlexusDx: Not confirmed
Zera Health: Not confirmed
Provider facts checked
PlexusDx: October 2026
Zera Health: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

PlexusDx

Shoppers who want one price at every dose, an oral option for either molecule, and all 50 states.

Reasons to consider it

  • LegitScript Certified, with the seal on the homepage
  • Same price at every dose, with no membership: semaglutide $189 and tirzepatide $289 month to month, less on 3- and 6-month plans
  • Both molecules come as weekly injections or daily tablets

What to weigh up

  • The 'starts at' $149 and $249 figures are 6-month-plan prices; month to month, semaglutide is $189 and tirzepatide $289
  • The tablets cost more than the shots: oral semaglutide starts at $249/mo and oral tirzepatide at $279/mo on the 6-month plan
  • No named prescriber, medical director, or specific compounding pharmacy

Compounded drugs are not FDA-approved. Understand the medication options.

Check PlexusDx pricing Read the full PlexusDx review

Zera Health

Shoppers who want a named 503A pharmacy and full 50-state coverage at a moderate compounded price.

Reasons to consider it

  • Named dispensing pharmacy — Strive Pharmacy, a 503A compounder — disclosed in the footer
  • LegitScript Certified badge displayed
  • States coverage across all 50 states with no exclusions listed

What to weigh up

  • First-month, monthly and quarterly prices differ; confirm your plan and second charge before paying
  • Quarterly plans require three months of payment at once
  • No individual prescriber or medical director is named

Compounded drugs are not FDA-approved. Understand the medication options.

Check Zera Health pricing Read the full Zera Health review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PlexusDxZera Health
Normalized Cost/Month
PlexusDx:
76/100
Zera Health:
73/100
Price Transparency
PlexusDx:
94/100
Zera Health:
92/100
Nationwide Access
PlexusDx:
86/100
Zera Health:
86/100
Formulation Options
PlexusDx:
77/100
Zera Health:
77/100
Clinical Oversight
PlexusDx:
74/100
Zera Health:
82/100
Contract Flexibility
PlexusDx:
55/100
Zera Health:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.