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WeighLab

PCOS Sisters vs Onyx Weight Loss

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

PCOS Sisters

Provider comparison

Women with PCOS who want GLP-1 prescribing folded into a specialty metabolic-care membership.

Semaglutide / month
Not disclosed
Tirzepatide / month
Not disclosed
Index 52/100 · Grade CChecked October 2026

Onyx Weight Loss

Provider comparison

Patients in one of its nine covered states who want a small clinic with scheduled consultations and ongoing provider support.

Semaglutide / month
Not disclosed
Tirzepatide / month
Not disclosed
Index 51/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

PCOS Sisters has the higher Cost-Efficiency Index: 52/100 versus 51/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

PCOS Sisters
12 states
Onyx Weight Loss
9 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

PCOS Sisters

Onyx Weight Loss

Semaglutide / month
PCOS Sisters: Not disclosed
Onyx Weight Loss: Not disclosed
Tirzepatide / month
PCOS Sisters: Not disclosed
Onyx Weight Loss: Not disclosed
Semaglutide / year (modeled)
PCOS Sisters: —
Onyx Weight Loss: —
Tirzepatide / year (modeled)
PCOS Sisters: —
Onyx Weight Loss: —
State availability
PCOS Sisters: 12 states
Onyx Weight Loss: 9 states
Oral / sublingual option listed
PCOS Sisters: Yes
Onyx Weight Loss: Not listed
Brand-name access listed
PCOS Sisters: Not confirmed
Onyx Weight Loss: Not confirmed
Provider facts checked
PCOS Sisters: October 2026
Onyx Weight Loss: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

PCOS Sisters

Women with PCOS who want GLP-1 prescribing folded into a specialty metabolic-care membership.

Reasons to consider it

  • Dedicated PCOS specialty model with a metabolic weight-loss program and fitness app bundled into the membership
  • Two named pharmacy partners with full addresses published (Strive Pharmacy, Gilbert AZ; Striker Pharmacy, Katy TX)
  • LegitScript and BBB verification badges both shown on its site

What to weigh up

  • A membership is required for a GLP-1 prescription, and medication, labs and imaging are billed separately by the pharmacy, lab or imaging center
  • Only some states are served, and you must choose a provider licensed in yours
  • Doesn't take Medicare or Medicaid; insurance is accepted only for Georgia evaluation visits

Onyx Weight Loss

Patients in one of its nine covered states who want a small clinic with scheduled consultations and ongoing provider support.

Reasons to consider it

  • Publishes a nine-state service list
  • Offers weight-loss, hormone and peptide services through one clinic
  • Names its founders and clinical team

What to weigh up

  • No GLP-1 program prices are published
  • No physician medical director or dispensing pharmacy is named
  • The oral weight-loss alternatives do not identify an oral GLP-1 medication

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PCOS SistersOnyx Weight Loss
Normalized Cost/Month
PCOS Sisters:
45/100
Onyx Weight Loss:
45/100
Price Transparency
PCOS Sisters:
54/100
Onyx Weight Loss:
54/100
Nationwide Access
PCOS Sisters:
52/100
Onyx Weight Loss:
42/100
Formulation Options
PCOS Sisters:
51/100
Onyx Weight Loss:
40/100
Clinical Oversight
PCOS Sisters:
70/100
Onyx Weight Loss:
76/100
Contract Flexibility
PCOS Sisters:
41/100
Onyx Weight Loss:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.