Best-value alternatives
Alternatives to PCOS Sisters
PCOS Sisters scores 52/100 on our Cost-Efficiency Index (ranked #390 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C52/ 100Index
Lyfe Rx
Ranked #389Lyfe Rx is a Shopify-based compounded-GLP-1 storefront charging a flat, all-inclusive $225/month for semaglutide and $299/month for tirzepatide with 'NO HIDDEN FEES OR MEMBERSHIPS,' shipping to 49 states (all but Alabama).
- Sema
- $225/mo (plus a separate fee, compounded)
- Tirz
- $299/mo (plus a separate fee, compounded)
- Coverage
- Multi-state
- Brand
- Compounded
Regulatory note: the FDA issued a warning letter to Lyfe Rx in September 2025. We still list and link to Lyfe Rx; you should know the letter is on the public record before you decide.
- 03C52/ 100Index
Hormonally Balanced
Ranked #388Hormonally Balanced is a Boston-based women's hormone and wellness telehealth practice led by CMO Dr. Andrew Lenhardt, serving seven states (MA, CA, TX, FL, NY, RI, NH).
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- All 50 states
- Brand
- Compounded
- 04C52/ 100Index
EllieMD
Ranked #387EllieMD is a women-focused telehealth weight-loss brand whose only publicly priced GLP-1 product is its microdosing program $229/mo for GLP-1 (semaglutide) and $239/mo for GLP-1/GIP (tirzepatide).
- Sema
- $229/mo (microdose tier, compounded)
- Tirz
- $239/mo (microdose tier, compounded)
- Coverage
- Multi-state
- Brand
- Yes
- 05C52/ 100Index
CVS MinuteClinic
Ranked #386CVS MinuteClinic is a general retail urgent-care service (in-store and some virtual) that can prescribe FDA-approved branded GLP-1s for weight loss 'when appropriate' as one of dozens of services it offers.
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- Multi-state
- Brand
- Yes
- 06C52/ 100Index
Alegro Health
Ranked #385Alegro Health is a McKinney, Texas telehealth practice offering compounded GLP-1 weight-loss care, advertised through a $199 8-week semaglutide-plus-B12 starter promo available only in select states.
- Sema
- $199/mo (starting dose, bundle, compounded)
- Tirz
- Not disclosed
- Coverage
- Multi-state
- Brand
- Compounded
- 07C52/ 100Index
Joi + Blokes
Ranked #384Joi + Blokes is a hormone-first telehealth platform running parallel women's (Joi) and men's (Blokes) programs, now including compounded GLP-1s at $199/mo semaglutide and $299/mo tirzepatide (after a discounted $99/$149 first month).
- Sema
- $199/mo (quarterly plan, compounded)
- Tirz
- $299/mo (quarterly plan, compounded)
- Coverage
- Multi-state
- Brand
- Compounded
Regulatory note: the FDA issued a warning letter to Joi and Blokes dba Joi + Blokes in June 2026. We still list and link to Joi + Blokes; you should know the letter is on the public record before you decide.
- 08C53/ 100Index
ZipHealth
Ranked #383ZipHealth is a compounded-GLP-1 telehealth platform delivering to 19 named states, advertising personalized programs 'from $149/month' but layering on a $79 clinical service fee that recurs on repeat visits, not just at signup.
- Sema
- $149/mo (starting dose, compounded)
- Tirz
- Not disclosed
- Coverage
- Multi-state
- Brand
- Yes
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.