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WeighLab

Onyx Weight Loss vs tru Weight Loss

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Onyx Weight Loss

Provider comparison

Patients in one of its nine covered states who want a small clinic with scheduled consultations and ongoing provider support.

Semaglutide / month
Not disclosed
Tirzepatide / month
Not disclosed
Index 51/100 · Grade CChecked October 2026

tru Weight Loss

Provider comparison

Patients comfortable committing to 3 months upfront who want a named, credentialed physician rather than an anonymous provider network.

Semaglutide / month
$299/mo3-month plan, compounded
Tirzepatide / month
$399/mo3-month plan, compounded
Index 51/100 · Grade CChecked August 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 51/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

Onyx Weight Loss
9 states
tru Weight Loss
Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Onyx Weight Loss

tru Weight Loss

Semaglutide / month
Onyx Weight Loss: Not disclosed
tru Weight Loss: $299/mo3-month plan, compounded
Tirzepatide / month
Onyx Weight Loss: Not disclosed
tru Weight Loss: $399/mo3-month plan, compounded
Semaglutide / year (modeled)
Onyx Weight Loss: —
tru Weight Loss: $3,588
Tirzepatide / year (modeled)
Onyx Weight Loss: —
tru Weight Loss: $4,788
State availability
Onyx Weight Loss: 9 states
tru Weight Loss: Coverage not published
Oral / sublingual option listed
Onyx Weight Loss: Not listed
tru Weight Loss: Not listed
Brand-name access listed
Onyx Weight Loss: Not confirmed
tru Weight Loss: Not confirmed
Provider facts checked
Onyx Weight Loss: October 2026
tru Weight Loss: August 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Onyx Weight Loss

Patients in one of its nine covered states who want a small clinic with scheduled consultations and ongoing provider support.

Reasons to consider it

  • Publishes a nine-state service list
  • Offers weight-loss, hormone and peptide services through one clinic
  • Names its founders and clinical team

What to weigh up

  • No GLP-1 program prices are published
  • No physician medical director or dispensing pharmacy is named
  • The oral weight-loss alternatives do not identify an oral GLP-1 medication

tru Weight Loss

Patients comfortable committing to 3 months upfront who want a named, credentialed physician rather than an anonymous provider network.

Reasons to consider it

  • Flat, clearly stated monthly pricing with no dose-tier increases
  • Named, credentialed medical director (Dr. Neha Grover, MD, obesity-management focus) rather than an anonymous network
  • Backed by an established local primary/urgent care practice, not a pure drop-ship telehealth startup

What to weigh up

  • Mandatory 3-month minimum commitment before cancellation is allowed -- roughly $900-$1,200 minimum spend
  • No insurance, HSA, or FSA accepted
  • Pharmacy partner not specifically named for the weight-loss program

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Onyx Weight Losstru Weight Loss
Normalized Cost/Month
Onyx Weight Loss:
45/100
tru Weight Loss:
35/100
Price Transparency
Onyx Weight Loss:
54/100
tru Weight Loss:
86/100
Nationwide Access
Onyx Weight Loss:
42/100
tru Weight Loss:
24/100
Formulation Options
Onyx Weight Loss:
40/100
tru Weight Loss:
66/100
Clinical Oversight
Onyx Weight Loss:
76/100
tru Weight Loss:
76/100
Contract Flexibility
Onyx Weight Loss:
55/100
tru Weight Loss:
20/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.