Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.
By The WeighLab Bench. Provider verification dates appear below.
Provider comparison
Shoppers comparing injectable and oral GLP-1 options who will confirm the price at their prescribed dose.
Compounded drugs are not FDA-approved. Understand the medication options.
Check Nucore Health pricing Read reviewAffiliate partner
Needle-averse shoppers who want a sublingual route on either molecule and will pay above the going rate for it, having accepted a three-month supply as the smallest unit sold.
Compounded drugs are not FDA-approved. Understand the medication options.
Check Direct Meds pricing Read reviewWe may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.
Nucore Health has the higher Cost-Efficiency Index: 74/100 versus 71/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.
Check the difference in state access
The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.
How the comparison is scoredPublished prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.
Nucore Health
Direct Meds
Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.
The strengths and limitations behind each provider's score. Read the full review before deciding.
Shoppers comparing injectable and oral GLP-1 options who will confirm the price at their prescribed dose.
Compounded drugs are not FDA-approved. Understand the medication options.
Check Nucore Health pricing Read the full Nucore Health reviewNeedle-averse shoppers who want a sublingual route on either molecule and will pay above the going rate for it, having accepted a three-month supply as the smallest unit sold.
Regulatory note: the FDA issued a warning letter to directmeds.com, Inc. dba DirectMeds in September 2025. We still list and link to Direct Meds; you should know the letter is on the public record before you decide.
Compounded drugs are not FDA-approved. Understand the medication options.
Check Direct Meds pricing Read the full Direct Meds reviewScores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.
Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.