Skip to content
WeighLab

Alternatives

Alternatives to Direct Meds

Direct Meds scores 71/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.

Read the Direct Meds review →CoreAge Rx vs Direct Meds →

Direct Meds at a glance

Semaglutide
$249/moSublingual, 90-day supply billed monthly
Tirzepatide
$299/moSublingual, 90-day supply billed monthly
Coverage
Not disclosed
Brand-name GLP-1s
No, compounded only
Oral option
Yes
Pricing verified
October 2026

6 of the 8 programs below list semaglutide for less than Direct Meds's $249 a month. 7 of the 8 list tirzepatide for less than its $299 a month.

Direct Meds sells semaglutide and tirzepatide both as a sublingual and as an injection, every product priced in the open, from $249 a month on a plan that bills against a 90-day supply.

Best for: Needle-averse shoppers who want a sublingual route on either molecule and will pay above the going rate for it, having accepted a three-month supply as the smallest unit sold.

What Direct Meds does well

  • Sublingual and injection on both molecules, so four GLP-1 products to choose from
  • Every price is published per SKU in a public shop, with no quiz, intake or email capture in front of it
  • Each product page prints a per-day equivalent beside the monthly rate ($8.03/day at $249), which is unusually concrete for this category
  • Free shipping, no monthly membership fee and no hidden fees are stated on every product page
  • Sermorelin and NAD+ sit in the same catalog for anyone already buying a GLP-1 there

Why readers look for an alternative

  • $249 a month for the sublingual and $297 for the injection cost more than many programs we track charge for an injection
  • The only purchasable option on every product page is a 90-DAY SUPPLY billed monthly, so three months is the smallest unit sold — there is no month-to-month rate to compare with programs you can cancel after one month
  • Every headline figure is framed "AS LOW AS", yet the only available option shows "0% OFF" — the framing implies a cheaper tier that is not actually on sale
  • No state list is published, so coverage cannot be checked before signing up
  • The compounding pharmacy is never named, so ask who fills your prescription
  • No FDA-approved brand-name route (no Wegovy, Ozempic, Mounjaro or Zepbound)
  • The site's own social proof does not agree with itself: the weight-loss page says "4.6" and "over 250,000+ happy customers", while the product pages say "4.5" and anywhere from "100,000+" to "290,000+ Happy Customers" — so we cite no customer count or rating for it at all
  1. Partner
    01A

    CoreAge Rx

    CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with Direct Meds: $150/mo less for semaglutide · $150/mo less for tirzepatide · no oral option

    Visit CoreAge Rx CoreAge Rx vs Direct Meds →
  2. 02C

    Gala Health

    Partner

    Every dose at one published price, with the whole price list visible before you hand over an email — but the only terms it sells on are a yearly subscription at $179 or a three-month plan at $199, so there is no monthly number here to compare with anyone else's.

    Sema
    From $129/moCompounded (plan length not stated); brand Ozempic $1,299/mo
    Tirz
    $179/moYearly subscription; $199/mo on a 3-month plan
    Coverage
    Multi-state
    Brand
    Yes

    Compared with Direct Meds: $120/mo less for tirzepatide · also lists brand-name GLP-1s · no oral option

    Visit Gala Health Gala Health vs Direct Meds →
  3. 03C

    DoctorAdam

    DoctorAdam is a Shopify-storefront telehealth company selling compounded oral (sublingual) and injectable semaglutide and tirzepatide plus NAD+/glutathione add-ons, prescribed by a named roster of six MD/NP prescribers.

    Sema
    $129/moStarting dose, compounded oral
    Tirz
    $199/moStarting dose, compounded oral
    Coverage
    44 states
    Brand
    Compounded

    Compared with Direct Meds: $120/mo less for semaglutide · $100/mo less for tirzepatide

    Visit DoctorAdam DoctorAdam vs Direct Meds →
  4. 04C

    Nu Image Medical

    Nu Image Medical offers compounded semaglutide and tirzepatide as injections or daily rapid-dissolve tablets, with advertised injection rates tied to a six-month supply.

    Sema
    $89/moAs low as, 6-month supply, compounded
    Tirz
    $89/moAs low as, 6-month supply, compounded
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with Direct Meds: $160/mo less for semaglutide · $210/mo less for tirzepatide

    Visit Nu Image Medical Nu Image Medical vs Direct Meds →
  5. 05C

    CoraDoc

    CoraDoc is a nationwide telehealth platform whose lowest advertised prices ($99/mo semaglutide, $149/mo tirzepatide) are one-time payments for a full 6-month program, not recurring monthly charges.

    Sema
    $99/moStarting dose, 6-month plan, compounded
    Tirz
    $149/mo6-month plan, compounded
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Direct Meds: $150/mo less for semaglutide · $150/mo less for tirzepatide · no oral option

    Visit CoraDoc CoraDoc vs Direct Meds →
  6. 06C

    Fitstry

    Fitstry, the GLP-1 program of the telehealth practice Weightstry, charges $249 every four weeks for compounded semaglutide, $339 for tirzepatide and $279 for a daily tablet, month to month, in 49 states.

    Sema
    $249Every 4 weeks (month-to-month, compounded; daily tablet $279)
    Tirz
    $339Every 4 weeks (month-to-month, compounded)
    Coverage
    49 states
    Brand
    Compounded

    Compared with Direct Meds: $40/mo more for tirzepatide

    Visit Fitstry Fitstry vs Direct Meds →
  7. 07C

    Nucore Health

    Nucore Health offers compounded semaglutide from $179 a month, tirzepatide from $269 and an oral semaglutide option from $209, with no membership fee.

    Sema
    $179/moAs low as; dose and plan terms need confirmation, compounded
    Tirz
    $269/moAs low as; dose and plan terms need confirmation, compounded
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with Direct Meds: $70/mo less for semaglutide · $30/mo less for tirzepatide

    Visit Nucore Health Nucore Health vs Direct Meds →
  8. 08C

    Roboclinic

    Roboclinic sells compounded semaglutide injections at $129 a month and tirzepatide at $189, the same price at every dose, with the consult, prescription and shipping included.

    Sema
    $129/mo1-month supply, same price every dose, compounded
    Tirz
    $189/mo1-month supply, same price every dose, compounded
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Direct Meds: $120/mo less for semaglutide · $110/mo less for tirzepatide

    Visit Roboclinic Roboclinic vs Direct Meds →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

← All comparisons & head-to-heads