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WeighLab

MyStart Health vs Roen Rx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

MyStart Health

Provider comparison

Shoppers who want a single flat all-inclusive monthly price and don't need semaglutide vs. tirzepatide broken out separately.

Semaglutide / month
$299/moCompounded
Tirzepatide / month
Not disclosed
Index 49/100 · Grade CChecked August 2026

Roen Rx

Provider comparison

Insured shoppers chasing a low brand-name copay through RoenRx's insurance help, with compounded semaglutide or tirzepatide as a fallback.

Semaglutide / month
$151/moStarting dose, 3-month plan, plus a separate fee, compounded
Tirzepatide / month
$216/moStarting dose, 3-month supply, plus a separate fee, compounded
Index 46/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

MyStart Health has the higher Cost-Efficiency Index: 49/100 versus 46/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

MyStart Health

Roen Rx

Semaglutide / month
MyStart Health: $299/moCompounded
Roen Rx: $151/moStarting dose, 3-month plan, plus a separate fee, compounded
Tirzepatide / month
MyStart Health: Not disclosed
Roen Rx: $216/moStarting dose, 3-month supply, plus a separate fee, compounded
Semaglutide / year (modeled)
MyStart Health: $3,588
Roen Rx: $1,812
Tirzepatide / year (modeled)
MyStart Health: —
Roen Rx: $2,592
State availability
MyStart Health: Coverage not published
Roen Rx: Coverage not published
Oral / sublingual option listed
MyStart Health: Not listed
Roen Rx: Not listed
Brand-name access listed
MyStart Health: Not confirmed
Roen Rx: Yes
Provider facts checked
MyStart Health: August 2026
Roen Rx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

MyStart Health

Shoppers who want a single flat all-inclusive monthly price and don't need semaglutide vs. tirzepatide broken out separately.

Reasons to consider it

  • Genuinely all-inclusive stated price: physician evaluations, unlimited follow-ups, bloodwork, and shipping are explicitly bundled into the $299 figure with 'no hidden fees'
  • Price-lock guarantee explicitly covers dose increases — the FAQ states the price won't rise 'even if your dosage increases'
  • Named Chief Medical Advisor (Dr. Ritu Chopra, Beverly Hills MD)

What to weigh up

  • Does not publish separate pricing for semaglutide vs. tirzepatide — $299 is a single blended program price, so it's unclear which drug (or whether both) that figure actually buys
  • A sitewide 'Lifetime 25% Off' promo banner is not reconciled against the stated '$299/month excluding any discounts' base price or the price-lock guarantee's 'excluding our first-time discount' exception — genuinely ambiguous what a patient ends up paying long-term
  • No compounding pharmacy named, only generic 'US facilities that meet strict USP standards'

Regulatory note: the FDA issued a warning letter to Matthew Stern, CEO MyStart Health LLC. in September 2025. We still list and link to MyStart Health; you should know the letter is on the public record before you decide.

Roen Rx

Insured shoppers chasing a low brand-name copay through RoenRx's insurance help, with compounded semaglutide or tirzepatide as a fallback.

Reasons to consider it

  • Insurance coordination path can bring brand-name GLP-1s down to as low as $25/mo for covered patients
  • Both compounded and brand-name (Ozempic, Wegovy, Zepbound, Mounjaro) options on one platform
  • Explicitly serves all 50 states and DC

What to weigh up

  • The LegitScript badge it advertises never actually appears on the homepage, so don't count it as certified until it shows you a certificate
  • Medication and membership are billed separately, and the membership's regular monthly price is never disclosed, only the '$39 first month' discount
  • The lowest medication price requires a 3-month prepay commitment, not a month-to-month rate

Regulatory note: the FDA issued a warning letter to Roen Health, Inc. dba RoenRx in June 2026. We still list and link to Roen Rx; you should know the letter is on the public record before you decide.

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

MyStart HealthRoen Rx
Normalized Cost/Month
MyStart Health:
35/100
Roen Rx:
24/100
Price Transparency
MyStart Health:
78/100
Roen Rx:
64/100
Nationwide Access
MyStart Health:
24/100
Roen Rx:
24/100
Formulation Options
MyStart Health:
53/100
Roen Rx:
79/100
Clinical Oversight
MyStart Health:
78/100
Roen Rx:
62/100
Contract Flexibility
MyStart Health:
31/100
Roen Rx:
33/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.