Head-to-head · Cost-Efficiency Index
Lyfe Rx vs Bloom MD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Lyfe Rx
Shoppers who want one flat all-inclusive charge with no separate membership fee, in 49 states.
Visit Lyfe RxBloom MD
Shoppers who want to see exact dose-by-dose pricing before signing up, for either compounded or branded GLP-1s.
Visit Bloom MDThe verdict
Lyfe Rx takes it, leading the Cost-Efficiency Index 52 to 51. Lyfe Rx is a Shopify-based compounded-GLP-1 storefront charging a flat, all-inclusive $225/month for semaglutide and $299/month for tirzepatide with 'NO HIDDEN FEES OR MEMBERSHIPS,' shipping to 49 states (all but Alabama). Bloom MD still earns a C — Shoppers who want to see exact dose-by-dose pricing before signing up, for either compounded or branded GLP-1s.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Lyfe Rx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Lyfe Rx | Bloom MD |
|---|---|---|
| Cost-Efficiency Index | 52/100 | 51/100 |
| Semaglutide / mo | $225/mo (plus a separate fee, compounded) | $295/mo (starting dose, plus a separate fee, compounded) |
| Tirzepatide / mo | $299/mo (plus a separate fee, compounded) | $295/mo (2.2 mg dose, plus a separate fee, compounded) |
| Semaglutide / yr (modeled) | $2,700 | $3,540 |
| Tirzepatide / yr (modeled) | $3,588 | $3,540 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #389 | #396 |
Lyfe Rx
52/100Where the value is
- Genuinely all-inclusive flat pricing — 'Every price covers your provider review, your medication, all medical supplies and free shipping,' with no separate membership charge unlike several competitors in this category
- 49-state coverage explicitly disclosed ('throughout the United States with the exception of Alabama')
- LegitScript Certified badge with a verification link displayed on the homepage
The tradeoffs
- No dose (mg) is shown on the semaglutide or tirzepatide product listing, so a shopper cannot tell what starting dose $225/$299 actually buys before starting the intake
- No compounding pharmacy is named beyond generic '503A pharmacy' language, and no medical director or prescriber is named anywhere on the site
Regulatory note: the FDA issued a warning letter to Lyfe Rx in September 2025. We still list and link to Lyfe Rx; you should know the letter is on the public record before you decide.
Bloom MD
51/100Where the value is
- Rare in this batch: publishes exact dollar pricing for every dose tier, pre-signup
- No hidden membership fee on compounded products -- price shown is the full price
- Offers both compounded AND branded (Wegovy/Zepbound) pathways
The tradeoffs
- No individual medical director named -- only a contracted provider group (MDI Medical Group PC)
- No compounding pharmacy named
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.