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Head-to-head · Cost-Efficiency Index

LillyDirect Foundayo vs LunaRx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #196

LillyDirect Foundayo

Patients who want an FDA-approved, manufacturer-direct oral GLP-1 rather than a compounded injectable.

Visit LillyDirect Foundayo
VS
Grade C · #197

LunaRx

Shoppers who value simple flat-rate pricing and a no-cost-if-declined guarantee over named clinical credentials.

Visit LunaRx

The verdict

Too close to callGrade C vs C

LillyDirect Foundayo and LunaRx tie on the Cost-Efficiency Index at 63/100, so neither wins outright on the numbers. For most shoppers we'd start with LillyDirect Foundayo (ranked #196, a hair above #197) — Patients who want an FDA-approved, manufacturer-direct oral GLP-1 rather than a compounded injectable. But LunaRx is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs LillyDirect Foundayo.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
70

Price Transparency

54
78

Nationwide Access

86
24

Formulation Options

69
66

Clinical Oversight

76
83

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecLillyDirect FoundayoLunaRx
Cost-Efficiency Index63/10063/100
Semaglutide / moNot disclosed$149/mo (compounded)
Tirzepatide / moNot disclosed$199/mo (compounded)
Semaglutide / yr (modeled)$1,788
Tirzepatide / yr (modeled)$2,388
CoverageAll 50 statesCoverage not published
Oral / sublingualYesNo
Brand-name accessYesCompounded only
Rank here#196#197

LillyDirect Foundayo

63/100

Where the value is

  • First-party Eli Lilly program -- highest possible manufacturer authenticity
  • FDA-approved branded drug (orforglipron), not an unapproved compounded formulation
  • Published self-pay starting price ($149) via savings card

The tradeoffs

  • Not semaglutide or tirzepatide -- a different molecule (orforglipron), so not directly comparable on this list
  • The $149 price is tied to a specific Savings Card program with its own terms, not an unconditional list price
Visit LillyDirect Foundayo

Full LillyDirect Foundayo review →

LunaRx

63/100

Where the value is

  • Advertises simple, flat-rate pricing with no hidden fees
  • '$0 if not approved' removes financial risk from a declined consult
  • Founder is publicly named (Anamaria Galvan, RN) rather than fully anonymous leadership

The tradeoffs

  • No named physician medical director -- only an RN founder is identified
  • No named compounding pharmacy partner
Visit LunaRx

Full LunaRx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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