Joi + Blokes vs Lean Rx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Joi + Blokes

Provider comparison

Patients already on Joi or Blokes hormone programs who want GLP-1 added under the same clinician relationship, and are comfortable with a 3-month billing commitment.

Semaglutide / month: $179/moBilled quarterly, first month $99, compounded
Tirzepatide / month: $249/moBilled quarterly, first month $149, compounded

Index 56/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Joi + Blokes pricing Read review

Lean Rx

Provider comparison

Shoppers who don't need transparency on credentials before comparing headline prices.

Semaglutide / month: $266/moStarting dose, compounded
Tirzepatide / month: $399/moStarting dose, compounded

Index 55/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Lean Rx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Joi + Blokes has the higher Cost-Efficiency Index: 56/100 versus 55/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Joi + Blokes

Lean Rx

Semaglutide / month: Joi + Blokes: $179/moBilled quarterly, first month $99, compounded; Lean Rx: $266/moStarting dose, compounded

Tirzepatide / month: Joi + Blokes: $249/moBilled quarterly, first month $149, compounded; Lean Rx: $399/moStarting dose, compounded

Semaglutide / year (modeled): Joi + Blokes: $2,148; Lean Rx: $3,192

Tirzepatide / year (modeled): Joi + Blokes: $2,988; Lean Rx: $4,788

State availability: Joi + Blokes: Coverage not published; Lean Rx: Coverage not published

Oral / sublingual option listed: Joi + Blokes: Not listed; Lean Rx: Not listed

Brand-name access listed: Joi + Blokes: Yes; Lean Rx: Not confirmed

Provider facts checked: Joi + Blokes: October 2026; Lean Rx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Joi + Blokes

Patients already on Joi or Blokes hormone programs who want GLP-1 added under the same clinician relationship, and are comfortable with a 3-month billing commitment.

Reasons to consider it

Named Medical Director, Dr. Melissa Loseke, DO, plus a named Head Nurse Practitioner and two named Medical Advisors, more clinical names than most programs we track
Separate gender-specific programs (Joi for women, Blokes for men) built around hormone health, with GLP-1 added as an integrated option alongside testosterone/perimenopause protocols
For FDA-approved GLP-1/GIP medications specifically, insurance is accepted and the prescription routes to the patient's own local pharmacy rather than a mail-order compounder

What to weigh up

Billed in 3-month blocks, not month-to-month — the $99/$149 first-month price is promotional, and the standing cost from month 2 is $179 (semaglutide) or $249 (tirzepatide)
New York and New Jersey residents are explicitly called out as paying different pricing, but the site does not state the amount
No full state-availability list is published — the safety page only says 'available in certain locations'

Regulatory note: the FDA issued a warning letter to Joi and Blokes dba Joi + Blokes in June 2026. We still list and link to Joi + Blokes; you should know the letter is on the public record before you decide.

Compounded drugs are not FDA-approved. Understand the medication options.

Check Joi + Blokes pricing Read the full Joi + Blokes review

Lean Rx

Shoppers who don't need transparency on credentials before comparing headline prices.

Reasons to consider it

Offers both semaglutide and tirzepatide
Simple, low headline starting prices
Straightforward telehealth consultation flow described

What to weigh up

No LegitScript certification displayed anywhere on the site
No named medical director or compounding pharmacy partner
No states-served list published

Compounded drugs are not FDA-approved. Understand the medication options.

Check Lean Rx pricing Read the full Lean Rx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Joi + BlokesLean Rx

Normalized Cost/Month: Joi + Blokes:
52/100; Lean Rx:
40/100

Price Transparency: Joi + Blokes:
78/100; Lean Rx:
78/100

Nationwide Access: Joi + Blokes:
24/100; Lean Rx:
24/100

Formulation Options: Joi + Blokes:
79/100; Lean Rx:
66/100

Clinical Oversight: Joi + Blokes:
82/100; Lean Rx:
80/100

Contract Flexibility: Joi + Blokes:
20/100; Lean Rx:
55/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.