Head-to-head · Cost-Efficiency Index
Joi + Blokes vs EllieMD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Joi + Blokes
Patients already on Joi or Blokes hormone programs who want GLP-1 added under the same clinician relationship, and are comfortable with a 3-month billing commitment.
Visit Joi + BlokesEllieMD
Shoppers specifically interested in a microdosing protocol with a named compounding pharmacy, not full-dose treatment.
Visit EllieMDThe verdict
Joi + Blokes and EllieMD tie on the Cost-Efficiency Index at 52/100, so neither wins outright on the numbers. For most shoppers we'd start with Joi + Blokes (ranked #384, a hair above #387) — Patients already on Joi or Blokes hormone programs who want GLP-1 added under the same clinician relationship, and are comfortable with a 3-month billing commitment. But EllieMD is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Joi + Blokes.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Joi + Blokes | EllieMD |
|---|---|---|
| Cost-Efficiency Index | 52/100 | 52/100 |
| Semaglutide / mo | $199/mo (quarterly plan, compounded) | $229/mo (microdose tier, compounded) |
| Tirzepatide / mo | $299/mo (quarterly plan, compounded) | $239/mo (microdose tier, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,748 |
| Tirzepatide / yr (modeled) | $3,588 | $2,868 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #384 | #387 |
Joi + Blokes
52/100Where the value is
- Named Medical Director, Dr. Melissa Loseke, DO, plus a named Head Nurse Practitioner and two named Medical Advisors — real clinical attribution not disclosed by most competitors in this batch
- Separate gender-specific programs (Joi for women, Blokes for men) built around hormone health, with GLP-1 added as an integrated option alongside testosterone/perimenopause protocols
- For FDA-approved GLP-1/GIP medications specifically, insurance is accepted and the prescription routes to the patient's own local pharmacy rather than a mail-order compounder
The tradeoffs
- Billed in 3-month blocks, not month-to-month — the $99/$149 first-month price is promotional, and the real standing cost from month 2 is $199 (semaglutide) or $299 (tirzepatide)
- New York and New Jersey residents are explicitly called out as paying different pricing, but the site does not state the amount
Regulatory note: the FDA issued a warning letter to Joi and Blokes dba Joi + Blokes in June 2026. We still list and link to Joi + Blokes; you should know the letter is on the public record before you decide.
EllieMD
52/100Where the value is
- Names its compounding pharmacy — Clover, a 503A facility — unlike most competitors in this batch that only say 'a licensed U.S. pharmacy'
- Explicitly states 'No hidden membership, shipping, or consultation fees' for the microdose program
- All 50 states served per the site's own claim
The tradeoffs
- The ONLY GLP-1 pricing published anywhere on the site is for the microdose program — a shopper wanting typical-dose semaglutide or tirzepatide will find no price before completing the intake process
- Microdose pricing requires a 12-week (84-day) minimum commitment; no month-to-month option was found
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.