Head-to-head · Cost-Efficiency Index
Genesis Lifestyle Medicine vs Framework
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Genesis Lifestyle Medicine
Cost-first shoppers who want in-person med-spa GLP-1 across a real multi-state footprint, if you're comfortable calling for pricing rather than seeing it online.
Visit Genesis Lifestyle MedicineFramework
Cost-first shoppers who want doctor-guided treatment selection with a named pharmacy, if you can accept learning the price only after intake.
Visit FrameworkThe verdict
Genesis Lifestyle Medicine takes it, leading the Cost-Efficiency Index 46 to 45. Genesis Lifestyle Medicine is a hybrid med-spa/telehealth chain with 16 physical locations across 8 states (TN, TX, NV, UT, IN, CO, FL, GA). Framework still earns a C — Cost-first shoppers who want doctor-guided treatment selection with a named pharmacy, if you can accept learning the price only after intake.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Genesis Lifestyle Medicine.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Genesis Lifestyle Medicine | Framework |
|---|---|---|
| Cost-Efficiency Index | 46/100 | 45/100 |
| Semaglutide / mo | Not disclosed | Not disclosed |
| Tirzepatide / mo | Not disclosed | Not disclosed |
| Semaglutide / yr (modeled) | — | — |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | 8 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #459 | #463 |
Genesis Lifestyle Medicine
46/100Where the value is
- 16 physical clinics confirmed by name across 8 states, allowing genuine in-person visits and injections rather than pure telehealth
- Confirmed dual modality — the nav explicitly lists both compounded semaglutide/tirzepatide and brand-name Wegovy/Zepbound on the same platform
- LegitScript verification badge displayed
The tradeoffs
- Zero pricing is published anywhere reached — /pricing and /weight-loss both 404, and the homepage gives no dollar figure for any of the five listed weight-loss products
- Location count could not be confirmed at the dataset's previously-recorded '18' — the live homepage states 16
Framework
45/100Where the value is
- The compounding pharmacy partner is named, which most of this field does not do
- Treatment selection is doctor-guided rather than a fixed product menu
- US-licensed clinicians and a 503A pharmacy pathway
The tradeoffs
- No monthly medication price is published: the tirzepatide and semaglutide pages carry no price at all, and the homepage advertises a per-week figure for 'GLP-1s' generally rather than a rate for either drug
- The only drug-specific prices anywhere on the site sit on a legacy page — semaglutide at $349 per three months and tirzepatide at $549 per three months
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.