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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs Genesis Lifestyle Medicine

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade C · #417

Genesis Lifestyle Medicine

Cost-first shoppers who want hybrid med-spa GLP-1 with 18 clinics and brand-name access.

Visit Genesis Lifestyle Medicine

The verdict

Winner · CoreAge RxGrade A vs C

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 46. Best value on the board: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Genesis Lifestyle Medicine still earns a CCost-first shoppers who want hybrid med-spa GLP-1 with 18 clinics and brand-name access.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
45

Price Transparency

97
20

Nationwide Access

98
42

Formulation Options

84
53

Clinical Oversight

90
78

Contract Flexibility

95
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxGenesis Lifestyle Medicine
Cost-Efficiency Index94/10046/100
Semaglutide / mo$149/moNot disclosed
Tirzepatide / mo$349/moNot disclosed
Semaglutide / yr (modeled)$1,788
Tirzepatide / yr (modeled)$4,188
CoverageAll 50 states8 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank on the board#1#417

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — cheaper teaser tiers exist (Direct GLP lists $65, Ondra $93 on semaglutide)
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

Genesis Lifestyle Medicine

46/100

Where the value is

  • 18 physical clinics allow in-person consults and injections across 8 states
  • Dual modality — compounded sema/tirz plus brand-name Wegovy and Zepbound on one platform
  • Med spa model lets patients combine weight loss, hormone therapy, and aesthetics

The tradeoffs

  • Pricing not disclosed publicly — gated behind the consultation flow
  • Specific 503A/503B pharmacy partner not named, and the designation not specified
Visit Genesis Lifestyle Medicine

Full Genesis Lifestyle Medicine review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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