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Alternatives

Alternatives to Framework

Framework scores 57/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.

Read the Framework review →CoreAge Rx vs Framework →

Framework at a glance

Semaglutide
Not disclosed
Tirzepatide
Not disclosed
Coverage
All 50 states and Puerto Rico (per terms)
Brand-name GLP-1s
No, compounded only
Oral option
No
Pricing verified
October 2026

Framework offers doctor-guided compounded GLP-1 plans with nutrition support, while the medication price appears after intake.

Best for: Patients who want clinician-guided treatment and nutrition support and can confirm the medication price before paying.

What Framework does well

  • Doctor-guided treatment selection
  • Nutrition support and regular clinician check-ins
  • Terms say service is available in all 50 states and Puerto Rico

Why readers look for an alternative

  • No monthly medication price is published: the tirzepatide and semaglutide pages carry no price at all, and the homepage advertises a per-week figure for 'GLP-1s' generally rather than a rate for either drug
  • The only drug-specific prices anywhere on the site sit on a legacy page — semaglutide at $349 per three months and tirzepatide at $549 per three months
  • A '$75/month with 3-month package' figure is footnoted as a promotion for new GLP-1 users only
  • Different landing pages advertise different per-week rates, $25 on one and $19 on another
  • Compounded semaglutide and tirzepatide are not FDA-approved finished products
  1. Partner
    01A

    CoreAge Rx

    CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded
    Visit CoreAge Rx CoreAge Rx vs Framework →
  2. 02C

    Coby Health

    Coby Health (Coby Health LLC) is a compounded-GLP-1 marketplace its own footer states 'Coby Health LLC operates as a marketplace, partnering with independent healthcare providers' rather than being the direct clinical provider.

    Sema
    $159/mo0.25 mg dose, bundle, compounded
    Tirz
    $239/mo2.5 mg dose, bundle, compounded
    Coverage
    46 states
    Brand
    Compounded
    Visit Coby Health Coby Health vs Framework →
  3. 03C

    Intimate Rose

    Intimate Rose offers an OpenLoop-supported compounded GLP-1 program from $169 monthly. That headline is not allocated to a specific medication or dose, so ask for an itemized quote.

    Sema
    Not separately disclosed (GLP-1 program from $169/mo)
    Tirz
    Not disclosed
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Framework: offers an oral option

    Visit Intimate Rose Intimate Rose vs Framework →

    Regulatory note: the FDA issued a warning letter to Intimate Rose in September 2025. We still list and link to Intimate Rose; you should know the letter is on the public record before you decide.

  4. 04C

    The Aesthetic Concierge

    The Aesthetic Concierge is a GLP-1 medical weight-loss and hormone-health telehealth provider led by named Medical Director Dr. Evan Blum, MD.

    Sema
    $414Every 5 weeks (compounded injection; $579 kick-off, confirm current renewal)
    Tirz
    From $479Every 5 weeks (compounded injection; dose bands apply, $579 kick-off)
    Coverage
    13 states
    Brand
    Yes

    Compared with Framework: also lists brand-name GLP-1s · offers an oral option

    Visit The Aesthetic Concierge The Aesthetic Concierge vs Framework →
  5. 05C

    LaSara Medical Group

    LaSara Medical Group offers compounded injections through Southern California clinics and telehealth, with monthly subscriptions at $289 for semaglutide and $379 for tirzepatide.

    Sema
    $289/moCompounded monthly subscription; $299 one-month purchase
    Tirz
    $379/moCompounded monthly subscription; $399 one-month purchase
    Coverage
    Multi-state
    Brand
    Compounded
    Visit LaSara Medical Group LaSara Medical Group vs Framework →
  6. 06C

    Red Mountain Weight Loss

    Red Mountain advertises GLP-1 medication from $149 a month, but you book a video or in-person visit first, labs are required, and the program and $99 consultation fees sit on top.

    Sema
    $149/moStarting price for its GLP-1 program; dose not stated, and program and lab fees are extra
    Tirz
    Not disclosed
    Coverage
    Multi-state
    Brand
    Compounded
    Visit Red Mountain Weight Loss Red Mountain Weight Loss vs Framework →
  7. 07C

    LumiMeds

    LumiMeds is a telehealth platform selling compounded semaglutide 'as low as $89/mo' and compounded tirzepatide 'as low as $125/mo' on fixed-term monthly, 3-, 6- and 12-month plans, with Klarna financing.

    Sema
    $89/moAs low as, fixed-term plan, plan length not stated, compounded; first month as low as $39
    Tirz
    $125/moAs low as, fixed-term plan, plan length not stated, compounded; first month as low as $75
    Coverage
    Multi-state
    Brand
    Compounded
    Visit LumiMeds LumiMeds vs Framework →

    Regulatory note: the FDA issued a warning letter to Lumimeds in September 2025. We still list and link to LumiMeds; you should know the letter is on the public record before you decide.

  8. 08C

    Emerge Weight Loss

    Emerge Weight Loss is a compounded-tirzepatide-only telehealth provider (no semaglutide) with dose-tiered 4-week pricing from $224 to $289 for injectable vials, plus a $149/month oral tablet option.

    Sema
    Not disclosed
    Tirz
    $224 per 4 weeks2.5 mg starting dose, compounded
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Framework: offers an oral option

    Visit Emerge Weight Loss Emerge Weight Loss vs Framework →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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