Enhance MD vs Trimi Health

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Enhance MD

Affiliate partner

Shoppers who want flat pricing that doesn't rise with the dose, routine lab monitoring and a semaglutide-plus-tirzepatide combo option, and who don't need a brand-name or oral route.

Semaglutide / month: $212/moFirst month $112
Tirzepatide / month: $280/moFirst month $180

Index 76/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Enhance MD pricing Read review

Trimi Health

Provider comparison

Shoppers who can pay a full year up front, and anyone else who will budget for the month-to-month price instead of the headline.

Semaglutide / month: $175/moMonth-to-month ($99/mo only on a 12-month prepay)
Tirzepatide / month: $235/moMonth-to-month ($125/mo only on a 12-month prepay)

Index 78/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Trimi Health pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Trimi Health has the higher Cost-Efficiency Index: 78/100 versus 76/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Enhance MD: 40 states + DC
Trimi Health: All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Enhance MD

Trimi Health

Semaglutide / month: Enhance MD: $212/moFirst month $112; Trimi Health: $175/moMonth-to-month ($99/mo only on a 12-month prepay)

Tirzepatide / month: Enhance MD: $280/moFirst month $180; Trimi Health: $235/moMonth-to-month ($125/mo only on a 12-month prepay)

Semaglutide / year (modeled): Enhance MD: $2,544; Trimi Health: $2,100

Tirzepatide / year (modeled): Enhance MD: $3,360; Trimi Health: $2,820

State availability: Enhance MD: 40 states + DC; Trimi Health: All 50 states

Oral / sublingual option listed: Enhance MD: Not listed; Trimi Health: Not listed

Brand-name access listed: Enhance MD: Not confirmed; Trimi Health: Not confirmed

Provider facts checked: Enhance MD: October 2026; Trimi Health: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Enhance MD

Shoppers who want flat pricing that doesn't rise with the dose, routine lab monitoring and a semaglutide-plus-tirzepatide combo option, and who don't need a brand-name or oral route.

Reasons to consider it

Every plan is priced on the homepage before any quiz: semaglutide $212, tirzepatide $280, a semaglutide-plus-tirzepatide combo $322 and microdosed tirzepatide $169
The monthly price stays the same as your dose goes up
Lab testing every six months and ongoing provider messaging are built into the price rather than sold separately

What to weigh up

Compounded only, with no brand-name Wegovy, Ozempic, Mounjaro or Zepbound
No oral or sublingual GLP-1, so every option is an injection
The $112 and $180 on the homepage are first-month prices; from month two you pay $212 and $280

Compounded drugs are not FDA-approved. Understand the medication options.

Check Enhance MD pricing Read the full Enhance MD review

Trimi Health

Shoppers who can pay a full year up front, and anyone else who will budget for the month-to-month price instead of the headline.

Reasons to consider it

All four plan lengths are priced on its pricing page: semaglutide is $175 monthly, $145 quarterly, $120 on six months and $99 on a year
Tirzepatide follows the same pattern: $235 monthly, $199 quarterly, $175 on six months and $125 on a year
Price is flat at every dose, so titrating up does not raise the bill

What to weigh up

The advertised $99 and $125 need a full year paid up front, $1,188 or $1,500; month to month costs $175 and $235
Compounded only, with no brand-name or oral option
A newer, lower-profile company with little public track record

Compounded drugs are not FDA-approved. Understand the medication options.

Check Trimi Health pricing Read the full Trimi Health review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Enhance MDTrimi Health

Normalized Cost/Month: Enhance MD:
65/100; Trimi Health:
61/100

Price Transparency: Enhance MD:
88/100; Trimi Health:
80/100

Nationwide Access: Enhance MD:
66/100; Trimi Health:
95/100

Formulation Options: Enhance MD:
74/100; Trimi Health:
76/100

Clinical Oversight: Enhance MD:
85/100; Trimi Health:
78/100

Contract Flexibility: Enhance MD:
82/100; Trimi Health:
82/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.