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Head-to-head · Cost-Efficiency Index

Effecty vs RxSpan MD

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B · #15

Effecty

People who want competitive compounded pricing but also the option to step up to brand-name, verified and nationwide.

Visit Effecty
VS
Grade B · #17

RxSpan MD

Someone who wants to compare a compounded route against brand-name Zepbound or Wegovy without leaving one provider, and who will read past the twelve-month figure.

Visit RxSpan MD

The verdict

Winner · EffectyGrade B vs B

Effecty takes it, leading the Cost-Efficiency Index 86 to 83. Mid-market compounded pricing plus FDA-approved brand access and LegitScript verification, nationwide — value with a safety-net formulary. RxSpan MD still earns a BSomeone who wants to compare a compounded route against brand-name Zepbound or Wegovy without leaving one provider, and who will read past the twelve-month figure.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Effecty.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

80
72

Price Transparency

86
84

Nationwide Access

96
88

Formulation Options

86
92

Clinical Oversight

88
86

Contract Flexibility

82
80

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecEffectyRxSpan MD
Cost-Efficiency Index86/10083/100
Semaglutide / mo$160/mo$249/mo month-to-month for the injection; $219 on three months, $199 on six and $194 on twelve
Tirzepatide / mo$240/mo$329/mo month-to-month for the injection; $309 on three months, $289 on six and $269 on twelve
Semaglutide / yr (modeled)$1,920$2,988
Tirzepatide / yr (modeled)$2,880$3,948
CoverageAll 50 statesAll 50 states
Oral / sublingualNoYes
Brand-name accessYesYes
Rank here#15#17

Effecty

86/100

Where the value is

  • Both molecules disclosed at competitive prices with all-50 access
  • Offers FDA-approved brand-name access alongside compounded
  • LegitScript-certified pharmacy

The tradeoffs

  • Per-month cost is mid-market, not budget-tier
  • No oral/sublingual option
Visit Effecty

Full Effecty review →

RxSpan MD

83/100

Where the value is

  • Every product and every term carries a published price, including the brand-name lane: Zepbound and Mounjaro at $1,069, Ozempic at $1,299 and Wegovy at $1,349
  • Five routes on one account — injection, oral capsule, orally dissolving tablet, microdose injection and brand — which is the broadest formulary of anything ranked here
  • A physician-founded program serving all 50 states

The tradeoffs

  • The storefront renders no price at all without JavaScript: the catalog is reachable, but a reader with a blocked script sees nothing
  • The figure a reader is most likely to meet elsewhere, around $194, is the twelve-month per-month rate; one month of the semaglutide injection is $249
Visit RxSpan MD

Full RxSpan MD review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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