Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.
By The WeighLab Bench. Provider verification dates appear below.
Affiliate partner
Needle-averse shoppers who want a sublingual route on either molecule and will pay above the going rate for it, having accepted a three-month supply as the smallest unit sold.
Compounded drugs are not FDA-approved. Understand the medication options.
Check Direct Meds pricing Read reviewProvider comparison
Patients in its 20 covered states who want ongoing care from the same nurse practitioner.
Compounded drugs are not FDA-approved. Understand the medication options.
Check Independent Wellness pricing Read reviewWe may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.
Independent Wellness has the higher Cost-Efficiency Index: 73/100 versus 71/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.
Check the difference in state access
The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.
How the comparison is scoredPublished prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.
Direct Meds
Independent Wellness
Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.
The strengths and limitations behind each provider's score. Read the full review before deciding.
Needle-averse shoppers who want a sublingual route on either molecule and will pay above the going rate for it, having accepted a three-month supply as the smallest unit sold.
Regulatory note: the FDA issued a warning letter to directmeds.com, Inc. dba DirectMeds in September 2025. We still list and link to Direct Meds; you should know the letter is on the public record before you decide.
Compounded drugs are not FDA-approved. Understand the medication options.
Check Direct Meds pricing Read the full Direct Meds reviewPatients in its 20 covered states who want ongoing care from the same nurse practitioner.
Compounded drugs are not FDA-approved. Understand the medication options.
Check Independent Wellness pricing Read the full Independent Wellness reviewScores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.
Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.