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WeighLab

CaliberRx vs ZYP Medical

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

CaliberRx

Provider comparison

Shoppers who want simple flat-rate pricing and a clear, published list of excluded states.

Semaglutide / month
$199/moAll doses, compounded
Tirzepatide / month
$199/moAll doses, compounded
Index 63/100 · Grade CChecked August 2026

ZYP Medical

Provider comparison

Readers in one of seven served states who want direct clinician contact and will confirm the consultation charge and refill price.

Semaglutide / month
Ongoing rate not published ($399 initial 10-week compounded injection course; plus a separate fee for consultation if applicable)
Tirzepatide / month
$250/moOral ODT (30-day supply, compounded); injectable starter $450 for 2 months; plus a separate fee for consultation if applicable
Index 63/100 · Grade CChecked October 2026

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The comparison in brief

Both score 63/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

CaliberRx
Coverage not published
ZYP Medical
7 states: NE, IA, SD, MN, KS, CO and AZ

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

CaliberRx

ZYP Medical

Semaglutide / month
CaliberRx: $199/moAll doses, compounded
ZYP Medical: Ongoing rate not published ($399 initial 10-week compounded injection course; plus a separate fee for consultation if applicable)
Tirzepatide / month
CaliberRx: $199/moAll doses, compounded
ZYP Medical: $250/moOral ODT (30-day supply, compounded); injectable starter $450 for 2 months; plus a separate fee for consultation if applicable
Semaglutide / year (modeled)
CaliberRx: $2,388
ZYP Medical: —
Tirzepatide / year (modeled)
CaliberRx: $2,388
ZYP Medical: $3,000
State availability
CaliberRx: Coverage not published
ZYP Medical: 7 states: NE, IA, SD, MN, KS, CO and AZ
Oral / sublingual option listed
CaliberRx: Not listed
ZYP Medical: Yes
Brand-name access listed
CaliberRx: Not confirmed
ZYP Medical: Not confirmed
Provider facts checked
CaliberRx: August 2026
ZYP Medical: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

CaliberRx

Shoppers who want simple flat-rate pricing and a clear, published list of excluded states.

Reasons to consider it

  • Flat, identical $199/month pricing for both semaglutide and tirzepatide -- no confusing dose tiers to compare
  • No prepay requirement or first-month-only price on the site
  • LegitScript certification verifiably linked

What to weigh up

  • No individual medical director named
  • No compounding pharmacy named
  • Not available in Alabama, Massachusetts, Rhode Island, or Vermont

ZYP Medical

Readers in one of seven served states who want direct clinician contact and will confirm the consultation charge and refill price.

Reasons to consider it

  • Names Josh Peterson, FNP-C as the treating clinician
  • Publishes full injection starter totals and a thirty-day oral ODT price
  • Names its seven states and Gretna, Nebraska office

What to weigh up

  • The semaglutide starter total does not establish a continuing monthly injection price
  • The weight-loss page advertises a free first consultation while the site footer lists $75 and $39.99 visits; confirm which applies
  • Refill cost depends on dose and order size

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

CaliberRxZYP Medical
Normalized Cost/Month
CaliberRx:
57/100
ZYP Medical:
47/100
Price Transparency
CaliberRx:
94/100
ZYP Medical:
86/100
Nationwide Access
CaliberRx:
24/100
ZYP Medical:
42/100
Formulation Options
CaliberRx:
66/100
ZYP Medical:
77/100
Clinical Oversight
CaliberRx:
88/100
ZYP Medical:
85/100
Contract Flexibility
CaliberRx:
47/100
ZYP Medical:
51/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.