Best-value alternatives
Alternatives to CaliberRx
CaliberRx scores 63/100 on our Cost-Efficiency Index (ranked #189 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C63/ 100Index
Blue Sky MD
Ranked #188Blue Sky MD is a physician-led medical weight-loss practice (founded 2008, LegitScript-certified, Medical Director Dr. David LaMond) with 7 physical clinics across North Carolina.
- Sema
- $160/mo (starting dose, compounded)
- Tirz
- $240/mo (starting dose, compounded)
- Coverage
- 1 state
- Brand
- Compounded
- 03C63/ 100Index
NativeMed
Ranked #187NativeMed is a direct-to-consumer telehealth site selling compounded semaglutide and compounded tirzepatide as flat-rate, any-dose weekly injections, with no membership fee and free 48-hour shipping advertised.
- Sema
- $149/mo (all doses, 3-month plan, compounded)
- Tirz
- $183/mo (all doses, 3-month plan, compounded)
- Coverage
- Multi-state
- Brand
- Compounded
Regulatory note: the FDA issued a warning letter to NativeMed LLC dba NativeMed in June 2026. We still list and link to NativeMed; you should know the letter is on the public record before you decide.
- 04C63/ 100Index
Zeuss
Ranked #186Zeuss (Zeuss LLC) is a compounded-GLP-1 telehealth brand marketed around avoiding 'subscription traps' — its FAQ states there are 'no recurring charges or automatic refills,' i.e.
- Sema
- $125/mo (starting dose, compounded)
- Tirz
- $175/mo (starting dose, compounded)
- Coverage
- Multi-state
- Brand
- Yes
Regulatory note: the FDA issued a warning letter to Zeuss LLC dba Zeuss in February 2026. We still list and link to Zeuss; you should know the letter is on the public record before you decide.
- 05C63/ 100Index
NexLife
Ranked #185NexLife is a LegitScript-certified compounded-GLP-1 and longevity telehealth platform under medical director Adam Kennah, M.D..
- Sema
- $165/mo (all doses, compounded)
- Tirz
- $215/mo (all doses, compounded)
- Coverage
- Multi-state
- Brand
- Compounded
Regulatory note: the FDA issued a warning letter to Nexlife Inc. dba Nexlife in June 2026. We still list and link to NexLife; you should know the letter is on the public record before you decide.
- 06C64/ 100Index
Bayan Health
Ranked #184Bayan Health prices compounded semaglutide at $129 and tirzepatide at $149 a month, flat at every dose, and also sells oral drops, low-dose programs and orforglipron tablets — but ships two to three months at a time and bills for the whole protocol.
- Sema
- $129.00/month billed monthly (standard injectable with vitamin B6; three months of medication ship at once)
- Tirz
- $149.00/month billed monthly (standard injectable with vitamin B6; same three-month protocol)
- Coverage
- Multi-state
- Brand
- Compounded
- 07C64/ 100Index
Nouri
Ranked #183Nouri is a 50-state GLP-1 telehealth provider prescribing through Wasef Health, PC (Dr. Michael Wasef, MD) and dispensing via 503A-licensed F&F Pharmacies dba Jungle Jim's Pharmacy (Fairfield, OH).
- Sema
- $175/mo (all doses, prepay plan, compounded)
- Tirz
- $225/mo (all doses, prepay plan, compounded)
- Coverage
- All 50 states
- Brand
- Compounded
- 08C64/ 100Index
Shapely
Ranked #182Shapely is primarily an insurance-navigation platform for branded GLP-1s, layering a separate monthly membership fee on top of medication cost.
- Sema
- $99/mo (plus a separate fee, compounded)
- Tirz
- $166/mo (plus a separate fee, compounded)
- Coverage
- 4 states
- Brand
- Yes
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.