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WeighLab

CaliberRx vs Ryze Rx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

CaliberRx

Provider comparison

Shoppers who want simple flat-rate pricing and a clear, published list of excluded states.

Semaglutide / month
$199/moAll doses, compounded
Tirzepatide / month
$199/moAll doses, compounded
Index 63/100 · Grade CChecked August 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check CaliberRx pricing Read review

Ryze Rx

Provider comparison

Shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.

Semaglutide / month
Not disclosedVials from $119; duration depends on dose
Tirzepatide / month
Not disclosedVials from $199; duration depends on dose
Index 63/100 · Grade CChecked October 2026
Check Ryze Rx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 63/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

CaliberRx
Coverage not published
Ryze Rx
All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

CaliberRx

Ryze Rx

Semaglutide / month
CaliberRx: $199/moAll doses, compounded
Ryze Rx: Not disclosedVials from $119; duration depends on dose
Tirzepatide / month
CaliberRx: $199/moAll doses, compounded
Ryze Rx: Not disclosedVials from $199; duration depends on dose
Semaglutide / year (modeled)
CaliberRx: $2,388
Ryze Rx: —
Tirzepatide / year (modeled)
CaliberRx: $2,388
Ryze Rx: —
State availability
CaliberRx: Coverage not published
Ryze Rx: All 50 states
Oral / sublingual option listed
CaliberRx: Not listed
Ryze Rx: Yes
Brand-name access listed
CaliberRx: Not confirmed
Ryze Rx: Not confirmed
Provider facts checked
CaliberRx: August 2026
Ryze Rx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

CaliberRx

Shoppers who want simple flat-rate pricing and a clear, published list of excluded states.

Reasons to consider it

  • Flat, identical $199/month pricing for both semaglutide and tirzepatide -- no confusing dose tiers to compare
  • No prepay requirement or first-month-only price on the site
  • LegitScript certification verifiably linked

What to weigh up

  • No individual medical director named
  • No compounding pharmacy named
  • Not available in Alabama, Massachusetts, Rhode Island, or Vermont

Compounded drugs are not FDA-approved. Understand the medication options.

Check CaliberRx pricing Read the full CaliberRx review

Ryze Rx

Shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.

Reasons to consider it

  • Lists injectable semaglutide and tirzepatide by vial strength, plus oral versions of both drugs
  • Physician consultation, ongoing clinical support and shipping are included
  • Licensed providers serve all 50 states

What to weigh up

  • The injectable catalog prices vials, so confirm how many weeks your prescription covers before treating a figure as a monthly cost
  • Pharmacy partners are not named
  • No detailed prescription refund policy is published
Check Ryze Rx pricing Read the full Ryze Rx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

CaliberRxRyze Rx
Normalized Cost/Month
CaliberRx:
57/100
Ryze Rx:
45/100
Price Transparency
CaliberRx:
94/100
Ryze Rx:
54/100
Nationwide Access
CaliberRx:
24/100
Ryze Rx:
86/100
Formulation Options
CaliberRx:
66/100
Ryze Rx:
51/100
Clinical Oversight
CaliberRx:
88/100
Ryze Rx:
80/100
Contract Flexibility
CaliberRx:
47/100
Ryze Rx:
77/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.