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WeighLab

TrimRx vs SkinnyRx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

TrimRx

Provider comparison

Shoppers who want one monthly package that covers the visit, the medication and shipping, and who will confirm the renewal price at checkout.

Semaglutide / month
$299/moMonth-to-month refill price; first month $199, compounded
Tirzepatide / month
$399/moMonth-to-month refill price; first month $349, compounded
Index 77/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check TrimRx pricing Read review

SkinnyRx

Affiliate partner

Shoppers who want a cheap first month to see how they tolerate a GLP-1, and who will budget for the price from month two.

Semaglutide / month
$249/moMonth to month after a $99 first month ($199/mo on a 12-month plan)
Tirzepatide / month
$299/moMonth to month after a $99 first month ($225/mo on a 12-month plan)
Index 74/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check SkinnyRx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

TrimRx has the higher Cost-Efficiency Index: 77/100 versus 74/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

TrimRx
All 50 states
SkinnyRx
Most states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

TrimRx

SkinnyRx

Semaglutide / month
TrimRx: $299/moMonth-to-month refill price; first month $199, compounded
SkinnyRx: $249/moMonth to month after a $99 first month ($199/mo on a 12-month plan)
Tirzepatide / month
TrimRx: $399/moMonth-to-month refill price; first month $349, compounded
SkinnyRx: $299/moMonth to month after a $99 first month ($225/mo on a 12-month plan)
Semaglutide / year (modeled)
TrimRx: $3,588
SkinnyRx: $2,988
Tirzepatide / year (modeled)
TrimRx: $4,788
SkinnyRx: $3,588
State availability
TrimRx: All 50 states
SkinnyRx: Most states
Oral / sublingual option listed
TrimRx: Not listed
SkinnyRx: Yes
Brand-name access listed
TrimRx: Yes
SkinnyRx: Not confirmed
Provider facts checked
TrimRx: October 2026
SkinnyRx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

TrimRx

Shoppers who want one monthly package that covers the visit, the medication and shipping, and who will confirm the renewal price at checkout.

Reasons to consider it

  • Each monthly package includes the telehealth consultation, the prescription, the medication and shipping, with no separate membership fee listed
  • The homepage promises the price stays the same as your dose goes up, and offers to keep your current dose if you switch from another program
  • Serves all 50 states, and the terms say so plainly

What to weigh up

  • The homepage says "Starting at $179" and "$259", but the terms list $199 and $349 for the first month and $299 and $399 for each follow-up month, so confirm which price applies to you before paying
  • Once your prescription is sent to the pharmacy that month's order can't be refunded; refunds on prepaid multi-month plans must be requested within 28 days of payment
  • The terms list Ozempic at $1,299 and Zepbound at $1,399 a month, while the site's footer says TrimRx doesn't sell or ship brand-name drugs, so ask how a brand prescription would be filled

Compounded drugs are not FDA-approved. Understand the medication options.

Check TrimRx pricing Read the full TrimRx review

SkinnyRx

Shoppers who want a cheap first month to see how they tolerate a GLP-1, and who will budget for the price from month two.

Reasons to consider it

  • The first month of either injection is $99, so trying the medication costs little
  • Prepaid plans lower the price: semaglutide renews at $225 a month on four months, $215 on six and $199 on twelve
  • Both compounded molecules come as a weekly injection or a daily tablet

What to weigh up

  • From month two the injection is $249 for semaglutide or $299 for tirzepatide, well above the $99 you see first
  • An FDA warning letter is on public record against Lean Rx, Inc. dba SkinnyRx, issued February 2026
  • Brand-name drugs appear in its catalog, but the Wegovy pill is listed as unavailable

Regulatory note: the FDA issued a warning letter to Lean Rx, Inc. dba SkinnyRx in February 2026. We still list and link to SkinnyRx; you should know the letter is on the public record before you decide.

Compounded drugs are not FDA-approved. Understand the medication options.

Check SkinnyRx pricing Read the full SkinnyRx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

TrimRxSkinnyRx
Normalized Cost/Month
TrimRx:
56/100
SkinnyRx:
71/100
Price Transparency
TrimRx:
94/100
SkinnyRx:
84/100
Nationwide Access
TrimRx:
86/100
SkinnyRx:
82/100
Formulation Options
TrimRx:
79/100
SkinnyRx:
73/100
Clinical Oversight
TrimRx:
85/100
SkinnyRx:
66/100
Contract Flexibility
TrimRx:
67/100
SkinnyRx:
58/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.