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Best-value alternatives

Alternatives to Science & Co

Science & Co scores 74/100 on our Cost-Efficiency Index (ranked #62 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.

  1. Our #1 pick
    01A

    CoreAge Rx

    Ranked #1

    Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded
  2. 02C

    NextMeds

    Ranked #61

    NextMeds is a compounded-GLP-1 telehealth platform naming a real clinical group (Lion MD, led by two NPI-verifiable physicians) and six named compounding pharmacies — unusually transparent on that front.

    Sema
    $79/mo (starting dose, promotional rate, compounded)
    Tirz
    $129/mo (starting dose, promotional rate, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
  3. 03C

    Nalena

    Ranked #60

    Nalena is a women-focused, GLP-1-only telehealth platform offering compounded semaglutide and tirzepatide with medication included — no separate membership or visit fees.

    Sema
    $149/mo (starting dose, compounded)
    Tirz
    $149/mo (starting dose, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
  4. 04C

    Jyra Health

    Ranked #59

    Jyra Health is a compounded GLP-1 telehealth clinic charging $175/mo (semaglutide) or $199/mo (tirzepatide) month-to-month, discounted to $139/mo and $179/mo respectively on a 3-month prepaid plan.

    Sema
    $175/mo (all doses, compounded)
    Tirz
    $199/mo (all doses, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
  5. 05C

    DoctorAdam

    Ranked #58

    DoctorAdam is a Shopify-storefront telehealth company selling compounded oral (sublingual) and injectable semaglutide and tirzepatide plus NAD+/glutathione add-ons, prescribed by a named roster of six MD/NP prescribers.

    Sema
    $129/mo (starting dose, compounded oral)
    Tirz
    $199/mo (starting dose, compounded oral)
    Coverage
    44 states
    Brand
    Compounded
  6. 06C

    Aspen

    Ranked #57

    Aspen Health (startaspen.com) is a cash-pay telehealth platform spanning weight loss, hair health, longevity, and sexual wellness.

    Sema
    $179/mo (all doses, compounded)
    Tirz
    $179/mo (all doses, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
  7. 07C

    Amble

    Ranked #56

    Amble is a managed-services telehealth platform (by its own terms, not itself a medical facility or pharmacy) selling compounded semaglutide and tirzepatide at IDENTICAL prices on a commitment-length pricing table: $179/mo with no commitment.

    Sema
    $179/mo (all doses, compounded)
    Tirz
    $179/mo (all doses, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
  8. 08C

    EdgeRx

    Ranked #55

    The best clinical documentation of any newly added row — a named Chief Medical Advisor and a named 503A pharmacy — but it's a men's-only platform, not a fit for every reader.

    Sema
    $229/mo (once-weekly injectable)
    Tirz
    $299/mo (once-weekly injectable)
    Coverage
    Multi-state
    Brand
    Compounded

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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